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From Synapses to Dynamics: Obtaining Function from Structure in a Connectome Constrained Model of the Head Direction Circuit

NeurIPS 2025 · Probabilistic and scientific modeling › Dynamical systems · approach: Recurrent circuit models of inference · 2 citations (OpenAlex)

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Builds a connectome-constrained model of the fly head direction circuit to test how far synaptic wiring determines network dynamics.

Problem

How precisely circuit wiring (synapse-resolution connectomes from EM) specifies circuit function and dynamics, and how far measured structure constrains dynamics.

Approach

Uses a connectome-constrained model of the head direction circuit to examine the extent to which measured synaptic structure determines the circuit's dynamical function.

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