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BenchX: A Unified Benchmark Framework for Medical Vision-Language Pretraining on Chest X-Rays

NeurIPS 2024 · Vision-language and multimodal › Human and embodied modeling · approach: Medical vision-language models · 1 citations (OpenAlex)

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Proposes BenchX, a unified benchmark framework that standardizes data, preprocessing, and task-adaptation protocols to fairly compare nine medical vision-language pretraining methods on chest X-ray classification, segmentation, report generation, and retrieval.

Problem

Existing medical vision-language pretraining (MedVLP) methods are evaluated with differing datasets, preprocessing, and finetuning setups, making fair head-to-head comparison on chest X-ray tasks impossible.

Approach

Pretrain all MedVLP methods on the same frontal MIMIC-CXR training split, standardize preprocessing and hyperparameter grid search, and use unified task heads (linear classifier, frozen-encoder UperNet for segmentation, frozen-encoder R2Gen for report generation) so that differences reflect the pretrained encoder; also shows that classification training tricks (LayerNorm, truncated normal init, di

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Add LN, TNI, and DLR instead of no refinements (ablation)ConVIRT · NIH classificationAUROC: 71.7 -> 77.0Helped
Apply DLR (ablation)ConVIRT · NIH classificationAUROC: 71.7 -> 76.9Helped
Add LN after DLR (ablation)ConVIRT · NIH classificationAUROC: 76.9 -> 74.5Hurt
Apply all refinements (ablation)MGCA-ViT · NIH classificationAUROC: 78.2 (=)No clear effect
Add LN, TNI, and DLR instead of no refinements (ablation)MRM · NIH classificationAUROC: 77.9 -> 80.1Helped
Add LN, TNI, and DLR instead of no refinements (ablation)REFERS · NIH classificationAUROC: 76.8 -> 75.6Hurt
Use TNI alone (ablation)MedVLP classification models · ClassificationAUROCHurt
Use ViT-based rather than ResNet-based encoderMedCLIP and MGCA · ClassificationAUROC or F1Helped
Use 10% rather than 100% of training dataMedVLP methods · All classification datasets except SIIMAUROC or F1No clear effect
Use MedVLP pretraining rather than the from-scratch baselineReport generation · IU-XrayBLEU4: 0.133$\pm$0.018 -> 0.148$\pm$0.006Helped
Use PTUnifier rather than the second-best methodImage-text retrieval · MIMIC 5x200H@1: 63.3 -> 78.7Helped
Use PTUnifier rather than MGCA-ViTImage-text retrieval · MIMIC 5x200P@5: 56.4 -> 38.4Hurt

Surprising findings

Limitations

Experimental setup

Datasets: MIMIC-CXR NIH ChestX-ray VinDr-CXR COVIDx CXR-4 SIIM-ACR Pneumothorax RSNA Pneumonia Object CXR TBX11K IU X-ray MIMIC 5x200

Benchmarks: NIH ChestX-ray VinDr-CXR COVIDx CXR-4 SIIM RSNA Pneumonia Object CXR TBX11K IU X-ray MIMIC 5x200

Metrics: AUROC F1 mDice BLEU ROUGE-L METEOR Hit@K Precision@K

Baselines: ConVIRT GLoRIA MedCLIP-R50 MedCLIP-ViT MedKLIP M-FLAG MGCA-R50 MGCA-ViT MRM PTUnifier REFERS

Builds on: ConVIRT GLoRIA MedCLIP MGCA MRM

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