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A World Model of Radiologist Reading for Medical Image Representation Learning
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Proposes GazeWorld, a gaze-ordered JEPA-style world model that predicts latent representations of successive radiologist-fixated patches (plus spatial completion of unvisited patches) to refine medical image encoders, evaluated on chest X-ray diagnosis and GazeSearch scanpath probing.
Problem
Existing medical imaging methods use radiologist gaze only as static spatial priors or as a scanpath prediction target decoupled from diagnosis, leaving the temporal order of expert evidence gathering unused for representation learning.
Approach
Treats the image as a world and the radiologist's fixation sequence as a trajectory; an autoregressive JEPA-style predictor predicts the EMA-target latent of the next fixated patch from prior fixations, combined with a cross-attention spatial-completion branch predicting unvisited patch latents.
Key results
- Frozen GazeWorld features achieve best supervised AUROC in all nine CheXpert/RSNA/SIIM-ACR label settings (e.g., CheXpert 1% 78.37 vs EGMA 71.21).
- On GazeSearch, the best GazeWorld variant reaches ScanMatch 0.489 vs 0.419 for LogitGaze-Med (CheX) and SED 3.63 vs 4.68.
- Zero-shot accuracy improves over MedCLIP initialization by about 2 to 10 points across the three datasets when GazeWorld is applied (e.g., SIIM-ACR accuracy 56.89 to 66.59).
Surprising findings
- Raster-scan or random fixation ordering substantially degrades zero-shot AUROC, below chance on several datasets (e.g., RSNA 50.39 raster-scan).
- A generic scanpath decoder on frozen GazeWorld features outperforms purpose-built LogitGaze-Med despite no explicit gaze prediction training.
Limitations
- Limited to chest radiographs and a single eye-tracking corpus (MIMIC-EYE).
- Evaluation of localization is qualitative only (Grad-CAM), with no clinician-centered study.
- Baseline numbers for several methods are taken from EGMA or original papers, and backbones differ (ResNet-50 vs Swin), confounding comparisons.
Experimental setup
Datasets: MIMIC-EYE MIMIC-CXR GazeSearch CheXpert RSNA Pneumonia SIIM-ACR Pneumothorax
Benchmarks: CheXpert RSNA Pneumonia SIIM-ACR Pneumothorax CheXpert 5x200 GazeSearch
Metrics: AUROC accuracy F1 ScanMatch SED STDE MultiMatch
Baselines: BioViL MedKLIP MGCA GLoRIA PRIOR MedCLIP CheXWorld EGMA GazeFormer HAT GazeSearch LogitGaze-Med
Builds on: JEPA MedCLIP EGMA LogitGaze-Med CheXWorld
Closest papers by meaning
- Mining Gaze for Contrastive Learning toward Computer-Assisted Diagnosis (AAAI 2024 · similarity 0.88)
- CheXWorld: Exploring Image World Modeling for Radiograph Representation Learning (CVPR 2025 · similarity 0.87)
- Eye-gaze Guided Multi-modal Alignment for Medical Representation Learning (NeurIPS 2024 · similarity 0.87)
- MedSIGHT: Towards Grounded Visual Comprehension in Medical Large Vision-Language Models (ICML 2026 · similarity 0.86)
- MedEyes: Learning Dynamic Visual Focus for Medical Progressive Diagnosis (AAAI 2026 · similarity 0.86)
- Large-scale and Fine-grained Vision-language Pre-training for Enhanced CT Image Understanding (ICLR 2025 · similarity 0.85)
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