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Coherent Hierarchical Multi-Label Learning to Defer for Medical Imaging
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Studies learning to defer over hierarchical multi-label taxonomies, showing naive per-node L2D yields deferral incoherence and proposing exact coherent projection (DP decoding) and Taxonomic Belief Propagation with Recursive Policy Optimisation (TBP+RPO) that drive incoherence near zero on CXR benchmarks.
Problem
Learning to defer in hierarchical multi-label settings can produce incoherent ternary (predict/defer) action vectors, such as taxonomic contradictions, delegation violations, and deductive defects, which are invisible to flat L2D and standard HMLC.
Approach
Formalises deferral coherence under a Selective-Exclusion handoff contract, gives an exact tree dynamic-programming projection onto coherent action vectors, and proposes a TBP transition model over actions trained end-to-end via RPO through the deployed recursion.
Key results
- On VinDr-CXR, BR+RPO reaches BalAcc 0.853 and F1-L 0.768 with near-zero incoherence (Any 0.004) while BR-L2D has Any 0.107.
- On CheXpert, BR+RPO improves BalAcc to 0.841 vs 0.811 for BR-L2D with Any incoherence ~0.
- BR+Projection gives exactly zero incoherence on all four datasets while staying utility-competitive with BR-L2D.
Surprising findings
- Continued BR training does not consistently reduce incoherence and can increase it (BR cont. Any 0.138 vs BR-L2D 0.107 on VinDr-CXR).
Limitations
- Only tree taxonomies studied; DAG extension discussed only in appendix.
- Evaluation uses retrospective annotations and controlled simulated experts rather than prospective deployment.
- Residual incoherence remains for the fast marginal decoder of TBP+RPO; exact MAP decoding trades off utility.
Experimental setup
Datasets: VinDr-CXR CheXpert PadChest ADPv2
Benchmarks: VinDr-CXR CheXpert PadChest ADPv2
Metrics: balanced accuracy F1-I F1-L taxonomic contradiction rate deductive defect rate delegation violation rate any incoherence rate
Baselines: BR-L2D BR (continued training) BR+Projection
Builds on: Learning to Defer Binary Relevance hierarchical multi-label classification
Closest papers by meaning
- Adaptive Labeling for Efficient Out-of-distribution Model Evaluation (NeurIPS 2024 · similarity 0.86)
- A Two-Stage Learning-to-Defer Approach for Multi-Task Learning (ICML 2025 · similarity 0.84)
- From Biased Selective Labels to Pseudo-Labels: An Expectation-Maximization Framework for Learning from Biased Decisions (ICML 2024 · similarity 0.84)
- Knowledge Transfer Scaling Laws for 3D Medical Imaging (NeurIPS 2026 · similarity 0.83)
- Bootstrapping Chest CT Image Understanding by Distilling Knowledge from X-ray Expert Models (CVPR 2024 · similarity 0.83)
- M3CoTBench: Benchmark Chain-of-Thought of MLLMs in Medical Image Understanding (ICLR 2026 · similarity 0.83)
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