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CellAgent: LLM-Driven Multi-Agent Framework for Natural Language-Based Single-Cell Analysis

ICLR 2026 · Multi-agent systems and games › LLM agents · approach: Agent data synthesis and behavior studies · 42 citations (OpenAlex)

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Introduces CellAgent, an autonomous LLM-driven multi-agent framework that lets researchers perform scRNA-seq and spatial transcriptomics analysis through natural language.

Problem

Single-cell RNA-seq and spatial transcriptomics analysis requires extensive manual programming and complex tool integration, which is a barrier for researchers.

Approach

An autonomous LLM-driven multi-agent system that translates natural-language requests into single-cell analysis workflows, removing the need for manual coding and tool integration.

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