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Ambient Diffusion Posterior Sampling: Solving Inverse Problems with Diffusion Models Trained on Corrupted Data

ICLR 2025 · Image generation › Fast diffusion sampling · approach: Diffusion posterior sampling · 0 citations (OpenAlex)

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Extends Ambient Diffusion to train MRI diffusion models from Fourier-subsampled multi-coil k-space and proposes Ambient DPS, a posterior sampler that uses such corrupted-data priors for inverse problems with different forward operators.

Problem

Solving inverse problems with diffusion priors when only linearly corrupted (e.g., Fourier subsampled MRI) training data is available, and whether priors trained on one corruption type can solve inverse problems with a different forward operator.

Approach

Replace the clean denoiser in Diffusion Posterior Sampling with an Ambient denoiser trained on corrupted measurements (with extra Fourier-domain line deletion), and apply it to arbitrary linear inverse problems; the paper also argues that priors trained on higher corruption can outperform clean-data priors at high acceleration.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Train the MRI diffusion prior on subsampled data and use A-DPS instead of clean-data FS-DPSMRI posterior sampling · Inference acceleration R=8Conditional FID: 4.16 -> 0.71Helped
Train the prior on subsampled MRI data at R=6 or R=8 instead of L1-Wavelet reconstructionsMRI unconditional generation · R=6 and R=8FID: 51.43 -> 31.50; 102.98 -> 48.15Helped
Train the prior on subsampled MRI data instead of clean dataMRI posterior reconstruction · High inference acceleration, R=8LPIPS: 0.231 -> 0.150Helped
Train the prior on subsampled MRI data instead of clean dataMRI posterior reconstruction · Low inference acceleration, R=2 and R=4NRMSE, SSIM, and PSNRHurt
Increase the training-data erasure probability (ablation)Ambient models on natural images · Compressed sensing at low measurement countsMSE and LPIPSHelped
Increase the training-data erasure probability (ablation)Ambient models on natural images · Compressed sensing at high measurement countsMSE and LPIPSHurt
Train with corrupted inpainted data rather than clean data (ablation)Natural-image restoration models · Super-resolution at 2xMSE and LPIPSHurt
Train with corrupted inpainted data rather than clean data (ablation)Natural-image restoration models · More severe downsamplingMSE and LPIPSHelped
Train with higher corruption rather than clean(er) data (ablation)Natural-image restoration models · Low NFEs, compressed sensing and downsamplingMSE and LPIPSHelped
Train with higher corruption rather than clean(er) data (ablation)Natural-image restoration models · Higher NFEs, compressed sensing and downsamplingMSE and LPIPSHurt
Use Ambient Diffusion rather than clean-data EDM for unconditional generationMRI diffusion models · R=2 and R=4FID: 10.41 -> 30.34; 10.41 -> 32.31Hurt

Surprising findings

Limitations

Experimental setup

Datasets: FastMRI T2-weighted brain multi-coil k-space CelebA FFHQ AFHQ abdominal MRI (undersampled, no ground truth)

Benchmarks: FastMRI brain reconstruction AFHQ CelebA FFHQ

Metrics: NRMSE SSIM PSNR LPIPS DISTS FID conditional FID MSE

Baselines: FS-DPS FS-ALD L1-Wavelet compressed sensing MoDL-Sup L1-DPS SSDU 1D-Partitioned SSDU A-ALD A-OS

Builds on: Ambient Diffusion Diffusion Posterior Sampling EDM Noisier2Noise SSDU

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