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TimeXL: Explainable Multi-modal Time Series Prediction with LLM-in-the-Loop

NeurIPS 2025 · Time series › Foundation models for time series · approach: LLM-based time series forecasting · 2 citations (OpenAlex)

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Proposes TimeXL, a multi-modal time series prediction framework combining a prototype-based explainable encoder with prediction, reflection, and refinement LLM agents in a closed loop, reporting gains in F1/AUC on four weather, finance, and healthcare datasets.

Problem

Multi-modal time series prediction methods fuse textual context for accuracy but offer little explicit reasoning about why or how contextual text affects outcomes, and they cannot easily explain predictions to users in high-stakes domains.

Approach

Couples a multi-modal prototype-based (case-based reasoning) encoder that yields predictions and prototype explanations with three GPT-4o-driven agents: a prediction LLM reasons over encoder explanations, a reflection LLM critiques predictions against ground truth, and a refinement LLM rewrites the text, which triggers encoder retraining in an iterative loop; final predictions fuse encoder and LLM

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
integrate time-series and text modalities in the encoder instead of using a time-series-only encoder (ablation)TimeXL encoder · Weather, Finance, Healthcare Test-Positive, Healthcare MortalityF1: 0.602 -> 0.674; 0.585 -> 0.619; 0.889 -> 0.934; 0.861 -> 0.937Helped
integrate time-series and text modalities in the encoder instead of using a text-only encoder (ablation)TimeXL encoder · Weather, Finance, Healthcare Test-Positive, Healthcare MortalityF1: 0.567 -> 0.674; 0.472 -> 0.619; 0.871 -> 0.934; 0.840 -> 0.937Helped
add prototype explanations to text-only LLM prediction (ablation)Prediction LLM · Weather, Finance, Healthcare Test-Positive, Healthcare MortalityF1: 0.645 -> 0.667; 0.496 -> 0.544; 0.974 -> 0.987; 0.901 -> 0.952Helped
fuse encoder and prediction LLM outputs rather than selecting the best component (ablation)TimeXL · Weather, Finance, Healthcare Test-Positive, Healthcare MortalityF1: 0.674 -> 0.696; 0.619 -> 0.631; 0.987 -> 0.987; 0.952 -> 0.956Mixed
use GPT-4o rather than GPT-4o-mini (ablation)TimeXL · Healthcare Test-PositiveF1: 0.932 -> 0.987Helped
use GPT-4o rather than Gemini-2.0-Flash (ablation)TimeXL · Healthcare Test-PositiveF1: 0.937 -> 0.987Helped
increase time-series prototype length from 1 to 5 (ablation)Multi-modal encoder · FinanceAUC: 0.595±0.002 -> 0.769±0.018Helped
vary prototype length across tested settings (ablation)Multi-modal encoder · WeatherAUC: 0.748±0.011; 0.754±0.008; 0.746±0.007; 0.743±0.007No clear effect
use regression TimeXL instead of TimeCAPTimeXL · Finance regressionRMSE: 4.456 -> 4.161Helped

Surprising findings

Limitations

Experimental setup

Datasets: Weather (New York, Kaggle historical hourly weather with summaries) Finance (raw material prices with 14 indices and news, extended from prior work) Healthcare Test-Positive (influenza, from TimeCAP) Healthcare Mortality (influenza and pneumonia, from TimeCAP)

Benchmarks: Weather Finance Healthcare Test-Positive Healthcare Mortality

Metrics: F1 AUROC RMSE MAE MAPE

Baselines: DLinear Autoformer Crossformer TimesNet iTransformer TSMixer TimeMixer FreTS PatchTST LLMTime PromptCast OFA

Builds on: TimeCAP Time-LLM ProtoPNet Sentence-BERT

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