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RETAIN: An Interpretable Predictive Model for Healthcare using Reverse Time Attention Mechanism

NeurIPS 2016 · Architectures and efficiency › RNNs and normalization · approach: Brain-inspired recurrent architectures · 220 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
temporal RNN models instead of stationary modelsLR/MLP · Heart failure prediction (Sutter)AUC: 0.7900 -> 0.8706Helped
MLP instead of LRaggregated-feature model · Heart failure prediction (Sutter)AUC: 0.7900 -> 0.8256Helped
RETAIN two-level attention vs plain RNNRNN · Heart failure prediction (Sutter)AUC: 0.8706 -> 0.8705No clear effect
RETAIN vs plain RNNRNN · Heart failure prediction (Sutter)test negative log-likelihood: 0.2577 -> 0.2562Helped
scalar visit attention generated by RNN (alpha_R) instead of MLP (alpha_M) (ablation)RNN+attention · Heart failure prediction (Sutter)AUC: 0.8624 -> 0.8717Helped
add vector-level beta attention to alpha_R (RETAIN) (ablation)RNN+alpha_R · Heart failure prediction (Sutter)AUC: 0.8717 -> 0.8705No clear effect
add beta attention to alpha_R (RETAIN) (ablation)RNN+alpha_R · Heart failure prediction (Sutter)test negative log-likelihood: 0.2605 -> 0.2562Helped
RETAIN vs RNN training costRNN · Heart failure prediction (Sutter)train time per epoch: 10.3s -> 10.8sHurt
RETAIN vs plain RNNRNN · Encounter diagnosis predictionRecall@10: 69.09 -> 67.74Hurt
RETAIN vs plain RNNRNN · Encounter diagnosis predictionRecall@5: 55.18 -> 54.25Hurt
RETAIN vs MLPMLP · Encounter diagnosis predictionRecall@10: 65.02 -> 67.74Helped
MLP vs RNN+alpha_M (stationary vs sequential)MLP · Encounter diagnosis predictionRecall@10: 65.02 -> 65.81No clear effect

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