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Prediction-Powered Adaptive Shrinkage Estimation

ICML 2025 · Probabilistic and scientific modeling › Molecules and proteins · approach: Prediction-powered and conformal inference · 0 citations (OpenAlex)

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Introduces Prediction-Powered Adaptive Shrinkage (PAS), which power-tunes PPI within each problem and then shrinks toward ML prediction means across many parallel mean-estimation problems, choosing the shrinkage by minimizing a correlation-aware unbiased risk estimate (CURE).

Problem

Estimating many parallel means (compound estimation) when gold-standard labels are scarce but ML predictions are available; existing PPI methods target single statistical problems and remain unbiased, leaving MSE gains on the table.

Approach

Combine within-problem power-tuned PPI (unbiased variance reduction) with across-problem empirical Bayes shrinkage toward the ML prediction mean, with a single global shrinkage parameter tuned by minimizing CURE, an unbiased estimate of compound risk that accounts for covariance between the shrinkage source and target.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Add adaptive shrinkage to PT (ablation)PAS · Synthetic, f1(x)=x²MSE (× 10^-3): 2.642 ± 0.027 -> 0.272 ± 0.003Helped
Add power tuning to shrink-classical estimator (ablation)PAS · Synthetic, f1(x)=x²MSE (× 10^-3): 0.272 ± 0.003 -> 0.272 ± 0.003No clear effect
Add adaptive shrinkage to PT (ablation)PAS · Synthetic, f2(x)=|x|MSE (× 10^-3): 2.659 ± 0.026 -> 2.466 ± 0.026Helped
Add power tuning to shrink-classical estimator (ablation)PAS · Synthetic, f2(x)=|x|MSE (× 10^-3): 2.863 ± 0.030 -> 2.466 ± 0.026Helped
Add adaptive shrinkage to PT (ablation)PAS · Amazon (base f; BERT-base)MSE (× 10^-3): 10.633 ± 0.089 -> 8.517 ± 0.071Helped
Add power tuning to shrink-classical estimator (ablation)PAS · Amazon (base f; BERT-base)MSE (× 10^-3): 15.995 ± 0.121 -> 8.517 ± 0.071Helped
Add adaptive shrinkage to PT (ablation)PAS · Amazon (tuned f; BERT-tuned)MSE (× 10^-3): 6.289 ± 0.050 -> 3.287 ± 0.024Helped
Add power tuning to shrink-classical estimator (ablation)PAS · Amazon (tuned f; BERT-tuned)MSE (× 10^-3): 3.828 ± 0.039 -> 3.287 ± 0.024Helped
Add adaptive shrinkage to PT (ablation)PAS · Galaxy Zoo 2 (WVT_BIN subgroups)MSE (× 10^-3): 1.026 ± 0.015 -> 0.893 ± 0.011Helped
Add power tuning to shrink-classical estimator (ablation)PAS · Galaxy Zoo 2 (WVT_BIN subgroups)MSE (× 10^-3): 1.522 ± 0.016 -> 0.893 ± 0.011Helped

Surprising findings

Limitations

Experimental setup

Datasets: Amazon Fine Food Reviews Galaxy Zoo 2 synthetic Gaussian model

Benchmarks: synthetic model Amazon Fine Food Reviews Galaxy Zoo 2 spiral fractions

Metrics: MSE % improved relative to classical estimator

Baselines: Classical estimator Prediction mean PPI PT (power-tuned PPI) Shrink-classical Shrink-average UniPT UniPAS

Builds on: Prediction-Powered Inference PPI++ James-Stein estimator Stein's unbiased risk estimate covariate-powered empirical Bayes

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