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Research map / Probabilistic and scientific modeling / Variational and generative sampling

Neural Markov Jump Processes

ICML 2023 · Probabilistic and scientific modeling › Variational and generative sampling · approach: Sequential Monte Carlo for inference · 0 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use irregular observation grids rather than regular gridsNeuralMJP on Discrete Flashing Ratchet · Discrete Flashing Ratchet parameter inferenceparameter recoveryHelped
Train NeuralMJP on the full ion-channel dataset instead of a one-second windowNeuralMJP · Switching ion channel stationary distributionstationary probabilities: Bottom: $0.17672$ -> $0.19631$; Middle: $0.09472 $ -> $0.07153 $; Top: $0.72856$ -> $0.73217$Mixed
Use two-step optimization, training encoder-decoder and prior parameters separately (ablation)NeuralMJP · Ground-truth MJP experimentsparameter recoveryHelped
Train encoder-decoder and prior parameters together in one back-propagation step (ablation)NeuralMJP · Ground-truth MJP experimentsparameter recoveryHurt
Replace explicit prior-rate parameters with a neural generator of rates (ablation)NeuralMJP · Prior transition-rate inferencetraining stabilityHelped
Use direct trainable prior-rate parameters instead of a neural generator (ablation)NeuralMJP · Prior transition-rate inferencetraining stabilityHurt
Add a Mercer time embedding to the posterior-rate network (ablation)NeuralMJP · Posterior dynamicslearned dynamicsHelped
Use augmented posterior dynamics to approximate the KL integral instead of Gaussian quadrature (ablation)NeuralMJP · KL approximationcomputational speedHurt
Use Tanh-Sinh quadrature instead of Gaussian quadrature (ablation)NeuralMJP · KL approximationcomputational efficiencyNo clear effect
Add an emission-covariance scheduler and gradually increase the number of observations during training (ablation)NeuralMJP with Gaussian emissions · Training stabilityindex collapse occurrenceHelped
Allow the KL regularization to jointly smooth posterior rates during training (ablation)NeuralMJP · Ground-truth MJP inferencetransition-rate recoveryHurt
Fit homogeneous prior MJPs to the optimized inhomogeneous posterior process in a separate step (ablation)NeuralMJP · Ground-truth MJP inferencetransition-rate recoveryHelped

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