Research map / Probabilistic and scientific modeling / Molecules and proteins
Continuous Time Bayesian Networks with Clocks
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Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| Use node-wise clocks with Weibull survival times instead of exponential survival times | CTBN structure inference · Synthetic Weibull trajectories | AUROC | Helped |
| Use node-wise clocks with Gamma survival times instead of exponential survival times | CTBN structure inference · Synthetic Gamma trajectories | AUROC | Helped |
| Use node-wise clocks with Gamma survival times instead of exponential survival times | CTBN structure inference · GeneNetWeaver E. coli gene regulatory network | edge prediction correctness | Helped |
| Increase the Weibull shape parameter away from the exponential case | Traditional CTBN structure inference · Synthetic Weibull trajectories with fixed shape | AUROC | Hurt |
| Use a Weibull CTBN rather than a traditional CTBN on exponential data | CTBN structure inference · Synthetic Weibull trajectories with shape k=1 | AUROC | No clear effect |
| Fit Weibull or Gamma survival-time parameters from more observed transitions | Augmented CTBN parameter inference · Synthetic trajectories | MSE | Helped |
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