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Research map / Probabilistic and scientific modeling / Molecules and proteins

Selective Inference for Sparse High-Order Interaction Models

ICML 2017 · Probabilistic and scientific modeling › Molecules and proteins · approach: Prediction-powered and conformal inference · 27 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
naive inference without selection bias correction (ablation)MS and OMP feature selection on synthetic data · synthetic FW-FPRfamily-wise false positive rateHurt
selective inference (conditioning on selection event) vs data splittingMS and OMP on synthetic data · synthetic TPRtrue positive rateHelped
tree-based pruning computational trick for selection event (ablation)MS selective inference · synthetic, d=100 to 10000, n up to 10000computation time (sec): e.g., d=100 n=10000 zeta=0.8: 1.98e4 s without vs 5.04 s withHelped
tree-based pruning computational trick for selection event (ablation)OMP selective inference · synthetic, d=100 to 10000, n up to 10000computation time (sec): e.g., n=100 d=100 zeta=0.8: 883 s without vs 0.233 s withHelped
selective inference on high-order interactions with d=10000, r=5, k=10 (MS)MS selective inference · HIV drug resistancenumber of Bonferroni-significant interactionsNo clear effect

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