Research map / Learning theory and algorithms / Fairness
FairSeg: A Large-Scale Medical Image Segmentation Dataset for Fairness Learning Using Segment Anything Model with Fair Error-Bound Scaling
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Introduces Harvard-FairSeg, a 10,000-subject SLO fundus optic disc/cup segmentation dataset with six sensitive attributes, and a fair error-bound scaling (FEBS) loss plus equity-scaled metrics (ES-Dice, ES-IoU) benchmarked on SAMed and TransUNet.
Problem
Existing medical fairness datasets target classification and lack sensitive-attribute annotations for segmentation, so fairness of medical segmentation models cannot be studied or compared, and classification-style fairness metrics are hard to interpret for segmentation.
Approach
Reweight the Dice loss per sensitive-attribute group using a tanh-scaled ratio of group losses (fair error-bound scaling) applied to SAMed, and define an equity-scaled metric ESSP = metric / (1 + sum of group-vs-overall disparities) to score fairness alongside accuracy.
Key results
- SAMed+FEBS achieves the best Rim ES-Dice of 0.7529 and ES-IoU of 0.6451 under race attribute, surpassing other SAMed-based methods.
- TransUNet+FEBS obtains the best Rim ES-Dice of 0.7050 (race) versus 0.7034 for TransUNet baseline.
- Under the language attribute, SAMed+ADV gives the best results among SAMed methods, and FEBS yields the top Cup ES-Dice of 0.8291 for SAMed.
Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| add FEBS to SAMed | SAMed · Harvard-FairSeg race, optic rim | ES-Dice: 0.7509 -> 0.7529 | Helped |
| add FEBS to TransUNet | TransUNet · Harvard-FairSeg race, optic rim | ES-Dice: 0.7034 -> 0.7050 | Helped |
| add FEBS to SAMed | SAMed · Harvard-FairSeg gender, optic cup and rim | ES-Dice: Cup: 0.8623 -> 0.8642; Rim: 0.8236 -> 0.8277 | Mixed |
| add FEBS to TransUNet | TransUNet · Harvard-FairSeg gender, optic cup and rim | ES-Dice: Cup: 0.8435 -> 0.8464; Rim: 0.7882 -> 0.7851 | Mixed |
| add FEBS to TransUNet | TransUNet · Harvard-FairSeg preferred language, optic cup and rim | ES-Dice: Cup: 0.8037 -> 0.8040; Rim: 0.7517 -> 0.7554 | Helped |
| add FEBS to SAMed | SAMed · Harvard-FairSeg preferred language, optic cup and rim | ES-Dice: Cup: 0.8186 -> 0.8291; Rim: 0.7852 -> 0.7892 | Mixed |
| add FEBS to SAMed | SAMed · Harvard-FairSeg ethnicity, optic cup and rim | ES-Dice: Cup: 0.8459 -> 0.8550; Rim: 0.8193 -> 0.8253 | Mixed |
| add FEBS to TransUNet | TransUNet · Harvard-FairSeg ethnicity, optic cup and rim | ES-Dice: Cup: 0.8281 -> 0.8320; Rim: 0.7815 -> 0.7857 | Mixed |
Surprising findings
- Adversarial and GroupDRO baselines often perform comparably to FEBS, and FEBS does not consistently win; for many attribute/metric combinations the differences are small (often <0.01).
- TransUNet-based methods underperform SAMed-based methods on Rim segmentation across attributes despite the same training setup.
Limitations
- Fairness gains from FEBS are marginal and not consistently superior to baselines.
- Segmentation labels are derived by registering OCT-derived masks to SLO images, with only about 80% registration success and manual filtering by five graders.
- Only SAMed and TransUNet are benchmarked, with a single disc-cup task on one imaging modality.
Experimental setup
Datasets: Harvard-FairSeg
Benchmarks: Harvard-FairSeg
Metrics: Dice IoU ES-Dice ES-IoU HD95 ASD NSD
Baselines: SAMed SAMed+ADV SAMed+GroupDRO TransUNet TransUNet+ADV TransUNet+GroupDRO
Builds on: Segment Anything Model SAMed TransUNet GroupDRO adversarially fair representations
Closest papers by meaning
- Distribution-aware Fairness Learning in Medical Image Segmentation From A Control-Theoretic Perspective (ICML 2025 · similarity 0.90)
- The Boundaries of Fair AI in Medical Image Prognosis: A Causal Perspective (NeurIPS 2025 · similarity 0.89)
- FairMedFM: Fairness Benchmarking for Medical Imaging Foundation Models (NeurIPS 2024 · similarity 0.89)
- FairCLIP: Harnessing Fairness in Vision-Language Learning (CVPR 2024 · similarity 0.88)
- FairTune: Optimizing Parameter Efficient Fine Tuning for Fairness in Medical Image Analysis (ICLR 2024 · similarity 0.88)
- Interactive Medical Image Segmentation: A Benchmark Dataset and Baseline (CVPR 2025 · similarity 0.85)
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