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Q-PART: Quasi-Periodic Adaptive Regression with Test-time Training for Pediatric Left Ventricular Ejection Fraction Regression

CVPR 2025 · Probabilistic and scientific modeling › Molecules and proteins · approach: Statistical analysis of ML practice · 3 citations (OpenAlex)

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Proposes Q-PART, a test-time training framework for pediatric LVEF regression that decomposes echocardiogram latents into periodic (helix trajectory) and aperiodic (Neural CDE) parts and minimizes prediction variance across ultrasound-specific augmentations at test time.

Problem

Adapting LVEF regression models to pediatric echocardiograms at test time, where existing TTT methods are designed for classification (entropy-based) and ignore the quasi-periodic nature of cardiac signals.

Approach

A Quasi-Period Network splits latent echo features into a periodic helix-trajectory component and an aperiodic Neural CDE component, and test-time adaptation uses a variance-minimization loss over augmented views with different BN learning rates for the two components.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Add QP-Net (ablation)Q-PART · Pre-SchoolMAE: 8.129 -> 7.949Helped
Add variance minimization to QP-Net (ablation)Q-PART · Pre-SchoolMAE: 7.949 -> 7.283Helped
Add the differential learning-rate strategy to QP-Net and VM (ablation)Q-PART · Pre-SchoolMAE: 7.283 -> 7.235Helped
Use Q-PART instead of TTT++pediatric LVEF regression · Pre-SchoolMAE: 8.053 -> 7.235Helped
Use Q-PART instead of NC-TTTpediatric LVEF regression · School AgeMAE: 7.285 -> 6.706Helped
Use Q-PART instead of NC-TTTpediatric LVEF regression · AdolescenceMAE: 7.422 -> 6.980Helped

Surprising findings

Limitations

Experimental setup

Datasets: EchoNet-Dynamic EchoNet-Pediatric

Benchmarks: EchoNet-Pediatric

Metrics: MAE RMSE MAPE mAUROC

Baselines: EchoNet MemSAM EchoCLIP Source-only TTT++ Clust3 NC-TTT

Builds on: Test-Time Training (TTT) TTT++ Tent Neural CDE EchoNet-Dynamic

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