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Learning the Graphical Structure of Electronic Health Records with Graph Convolutional Transformer

AAAI 2020 · Graph learning › Graph self-supervised learning · approach: Brain and biological graph learning · 250 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Combine conditional-probability guidance with masked, learned self-attentionTransformer for synthetic graph reconstruction · Synthetic graph reconstruction testAUCPR: 0.5752 (0.0015) -> 0.5965 (0.0031)Helped
Use conditional-probability guidance and masked, learned self-attention instead of a shallow bag-of-features modelSynthetic diagnosis-treatment classification · Synthetic diagnosis-treatment classification testAUCPR: 0.8555 (0.0206) -> 0.8671 (0.0247)Helped
Use learned structure without access to the true adjacency matrixGCT on synthetic masked diagnosis prediction · Synthetic masked diagnosis code prediction testaccuracy: 0.2834 (0.0065) -> 0.2179 (0.0071)Hurt
Combine conditional-probability guidance with learned attentionGCN_P on eICU masked diagnosis prediction · eICU masked diagnosis code prediction testaccuracy: 0.7432 (0.0086) -> 0.7704 (0.0039)Helped
Learn latent encounter structure with GCT rather than using a deep feedforward bag-of-features modeleICU readmission prediction · eICU readmission prediction testAUCPR: 0.5050 (0.0126) -> 0.5244 (0.0142)Helped
Learn latent encounter structure with GCT rather than using a deep feedforward bag-of-features modeleICU mortality prediction · eICU mortality prediction testAUCPR: 0.5924 (0.0121) -> 0.5992 (0.0223)Helped
Use conditional probabilities instead of unguided Transformer attentionSynthetic structure learning · Synthetic graph reconstruction, diagnosis-treatment classification, and masked diagnosis predictionKL divergence to true adjacency: 19.6268 (2.9114) -> 7.6490 (0.0476); 14.3178 (0.2084) -> 8.0363 (0.0305); 15.1837 (0.8646) -> 8.9648 (0.1944)Helped
Use latent encounter structure for mortality predictionGCT versus Deep on eICU · eICU mortality prediction testAUROC: 0.9092 (0.0060) -> 0.9120 (0.0048)Mixed

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