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Hierarchical Divide-and-Conquer for Fine-Grained Alignment in LLM-Based Medical Evaluation

AAAI 2025 · Large language models › Agents, code and math · approach: Mathematical and structural reasoning benchmarks · 1 citations (OpenAlex)

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Proposes HDCEval, a hierarchical divide-and-conquer framework where specialized MedLlama2-7B evaluator models per medical evaluation aspect are trained with ADTO (reward-token preference optimization) on a 13,452-sample preference dataset to better align with physicians.

Problem

LLM-based evaluators and traditional metrics are misaligned with human physicians and give oversimplified assessments when evaluating freestyle medical responses from medical LLMs.

Approach

Decompose medical evaluation into primary aspects (REL, COR, EXP) and subtasks, assign each to a separate expert evaluator trained with Attribute-Driven Token Optimization, which conditions a DPO-style preference loss on aspect-specific reward tokens and freezes the first 24 layers.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Add reward tokens during training (ablation)HDCEval · Fine-grained medical evaluationEvaluation accuracy: 75.13 -> 72.01Helped
Use preference data with ADTO rather than only SFT (ablation)HDCEval · Fine-grained medical evaluationEvaluation accuracy: 75.13 -> 73.13Helped
Train with preference dataHDCEval · Patient Question Relevance (CONT, COND, CONC)Position and verbosity bias: Position Bias: CONT 32.91 -> 28.57; COND 31.82 -> 26.50; CONC 32.91 -> 29.87; Verbosity Bias: CONT 32.96 -> 28.17; COND Helped
Use different input formats: jointly evaluate two responses versus evaluate separately then compareHDCEval · Medical evaluationEvaluation resultsNo clear effect
Use HDCEval instead of PandaLMMedical evaluation across scenarios · Medical evaluationPairwise accuracy: 23.92%Helped

Surprising findings

Limitations

Experimental setup

Datasets: medical meadow wikidoc MedBench MedText MedDialog MedMCQA

Benchmarks: HDCEval medical evaluation test set

Metrics: pairwise accuracy reference match pearson correlation intraclass correlation coefficient win-tie-lose

Baselines: GPT-4 ChatGPT PandaLM MedLlama2 BSM

Builds on: direct preference optimization BSM PandaLM FlashAttention Fully Sharded Data Parallel

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