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TopoFisher: Learning Topological Summary Statistics by Maximizing Fisher Information

NeurIPS 2026 · Probabilistic and scientific modeling › Uncertainty and Gaussian processes · approach: Nonparametric and PAC-Bayes Bayesian learning · 0 citations (OpenAlex)

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Proposes TopoFisher, a differentiable persistent-homology pipeline whose trainable filtrations, vectorizations and compressors are optimized to maximize local Gaussian Fisher information, with a Lipschitz stability result and experiments on spirals, GRFs and weak lensing.

Problem

Persistence-based summaries for simulation-based inference require hand-chosen filtrations, vectorizations and compressors without an objective tied to parameter uncertainty.

Approach

Train the full persistence pipeline (filtration, vectorization, compressor) by minimizing the negative log-determinant of a local Gaussian Fisher matrix estimated from simulations at a fiducial parameter, and prove local Lipschitz continuity of this loss under regularity assumptions.

Key results

Surprising findings

Limitations

Experimental setup

Datasets: noisy spiral point clouds (simulated) Gaussian random fields (simulated) sbi_lens lognormal and LPT convergence maps

Benchmarks: noisy spirals Gaussian random fields weak lensing local Fisher weak lensing transfer Fisher weak lensing NPE posterior

Metrics: log|F| marginal constraints sigma efficiency eta_log

Baselines: IMNN power spectrum peak counts wavelet scattering transform DTM Cubical-PI Cubical-Silhouette Cubical-Curves MLP-only GNN-only

Builds on: PersLay IMNN MOPED persistence images differentiable persistent homology

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