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Learning What's Real: Disentangling Signals and Measurement Artifacts in Multi-Sensor Data, with Applications to Astrophysics

NeurIPS 2026 · Label-efficient and robust learning › Self-supervised and contrastive · approach: Invariance-based self-supervised learning

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Proposes a dual-encoder conditional flow-matching model that separates physics and instrument latents from overlapping multi-instrument galaxy images (HSC and Legacy), using counterfactual generation as the training objective.

Problem

Observations are confounded by instrument-specific artifacts, which hinder extracting physical signals and combining heterogeneous multi-instrument data; standard foundation models treat instruments as independent modalities without disentangling them.

Approach

Train two ResNet-18 encoders (physics encoder on the same source from another instrument; instrument encoder on other sources from the same instrument) whose latents condition a flow-matching decoder that reconstructs an anchor observation never fed to the encoders, so disentanglement emerges from the counterfactual generation objective rather than contrastive or hand-designed losses.

Key results

Surprising findings

Limitations

Experimental setup

Datasets: Multimodal Universe cross-matched HSC and DESI Legacy Imaging Survey galaxy images PROVABGS catalogue HSC shape catalog

Benchmarks: Multi-instrument galaxy probe tasks (MLP R^2 on physics and instrument properties) Outlier detection on HSC galaxies Cross-instrument reconstruction MSE

Metrics: R^2 MSE log-likelihood (outlier score) power spectral density agreement pixel-wise Z-score calibration

Baselines: AION-1 AstroCLIP randomly initialized ResNet-18 cross-predict ResNet

Builds on: flow matching beta-VAE AION-1 UNet2DConditionModel ResNet

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