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GraphBridge: Towards Arbitrary Transfer Learning in GNNs

ICLR 2025 · Graph learning › Graph self-supervised learning · approach: Graph domain adaptation · 0 citations (OpenAlex)

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Proposes GraphBridge, a side-tuning framework (GSST and GMST) that adapts pre-trained GNNs to arbitrary graph tasks and domains (graph, node, point cloud) with input/output bridges and a small trainable side network.

Problem

Pre-trained GNNs are typically tied to a single domain and task format, so transferring them to tasks with different input/output dimensions and across large domain gaps suffers from heterogeneity and negative transfer.

Approach

Wrap any frozen pre-trained GNN with input adapters, task-specific prediction heads, and a trainable side network; GSST fuses layer-wise activations with a random MLP side network, while GMST additionally merges the pre-trained backbone with a randomly initialized backup model to dilute source bias.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use GSST instead of fine-tuningGraphCL-pretrained GIN · Graph2Graph molecular benchmarks (average)ROC-AUC (%): 70.3 -> 70.9Helped
Use GSST instead of fine-tuningSimGRACE-pretrained GIN · Graph2Graph molecular benchmarks (average)ROC-AUC (%): 66.3 -> 66.4No clear effect
Use GMST instead of training from scratchGraphCL-pretrained GIN · CiteSeeraccuracy (%): 55.10 -> 58.80Helped
Use GMST instead of fine-tuningGraphCL-pretrained GIN · PubMedaccuracy (%): 67.30 -> 72.60Helped
Use GMST instead of fine-tuningGraphCL-pretrained GCN · Cora, Node2Nodeaccuracy (%): 74.40 -> 73.10Hurt
Use GMST instead of fine-tuningGraphCL-pretrained GCN · CiteSeer, Graph2Nodeaccuracy (%): 52.60 -> 61.90Helped
Use GSST instead of fine-tuningGraphCL-pretrained GCN · ModelNet10 transfer from ogbg-molhivaccuracy (%): 78.1 er{\color{gray}±1.7} -> 81.7 er{\color{gray}±2.9}Helped
Add GSST tuning rather than direct inference (ablation)GraphCL-pretrained model · Cora, node-level pre-training, GCNaccuracy (%): 13.80 -> 63.30Helped
Add GMST tuning rather than direct inference (ablation)GraphCL-pretrained model · Cora, node-level pre-training, GCNaccuracy (%): 13.80 -> 73.10Helped
Add GMST tuning rather than direct inference (ablation)GraphCL-pretrained model · Cora, graph-level pre-training, GCNaccuracy (%): 13.50 -> 74.80Helped
Add GSST tuning rather than direct inference (ablation)GraphCL-pretrained model · Cora, graph-level pre-training, GCNaccuracy (%): 13.50 -> 52.20Helped

Surprising findings

Limitations

Experimental setup

Datasets: ZINC-full BACE BBBP ClinTox HIV SIDER Tox21 MUV ToxCast ogbn-arxiv Cora CiteSeer

Benchmarks: BACE BBBP ClinTox HIV SIDER Tox21 MUV ToxCast Cora CiteSeer PubMed Amazon-Computers

Metrics: ROC-AUC test accuracy

Baselines: Full fine-tuning MetaGP MetaFP Adapter-GNN GBST GAST

Builds on: side-tuning GraphCL SimGRACE MetaFP Adapter-GNN

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