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Conditional Testing based on Localized Conformal $p$-values

ICLR 2025 · Probabilistic and scientific modeling › Molecules and proteins · approach: Prediction-powered and conformal inference · 0 citations (OpenAlex)

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Defines localized conformal p-values by inverting randomly localized conformal prediction intervals and applies them to conditional outlier detection (FDR), conditional label screening (FWER), and two-sample conditional distribution testing via a weighted U-statistic.

Problem

Conditional testing problems (outlier detection, label screening, two-sample conditional distribution testing) where standard conformal p-values target the marginal rather than the conditional distribution, so they lack power and conditional error control.

Approach

Localized conformal p-values are built by inverting randomly localized conformal prediction intervals, using kernel-weighted empirical distributions over calibration scores, so the p-value adapts to the conditional distribution of the score given covariates while keeping finite-sample validity via a random covariate draw.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use localized conformal p-values instead of unweighted conformal p-valuesConditional outlier detection with CQR-QRF · House Sales, quantile-based outliers, α=0.15Power: 0.858 (0.070) -> 0.871 (0.048)Helped
Use localized conformal p-values instead of unweighted conformal p-valuesConditional outlier detection with CQR-QRF · House Sales, quantile-based outliers, α=0.2Power: 0.907 (0.022) -> 0.913 (0.021)Helped
Use localized conformal p-values instead of unweighted conformal p-valuesConditional outlier detection with CQR-QRF · House Sales, variance-based outliers, α=0.15Power: 0.581 (0.119) -> 0.628 (0.092)Helped
Use localized conformal p-values instead of unweighted conformal p-valuesConditional outlier detection with CQR-QRF · House Sales, variance-based outliers, α=0.2Power: 0.692 (0.106) -> 0.722 (0.056)Helped
Use localized p-values instead of unweighted CP thresholdingConditional label screening with LL · Health indicatorsConditional FWER: 0.0740 (0.028) -> 0.0329 (0.018)Helped
Use localized p-values instead of unweighted CP thresholdingConditional label screening with RF · Health indicatorsConditional FWER: 0.0887 (0.029) -> 0.0372 (0.018)Helped
Use localized conformal testing instead of CTTwo-sample conditional distribution test · Airfoil, Case (i), NNRejection proportion: 0.441 (0.0610) -> 0.053 (0.0374)Helped
Use localized conformal testing instead of CTTwo-sample conditional distribution test · Airfoil, Case (ii), NNRejection proportion: 0.135 (0.0405) -> 0.066 (0.0390)Helped
Use localized conformal testing instead of DCTTwo-sample conditional distribution test · Airfoil, Case (iii), NNMedian p-value: 0.018 -> 0.000Helped
Use localized conformal testing instead of DCTTwo-sample conditional distribution test · Airfoil, Case (iii), LLMedian p-value: 0.000 -> 0.000No clear effect
Use localized conformal p-values instead of unweighted CP p-valuesConditional outlier detection with CQR-QNN · House Sales, quantile-based outliers, α=0.15Power: 0.593 (0.037) -> 0.657 (0.096)Helped

Surprising findings

Limitations

Experimental setup

Datasets: House Sales in King County Health indicators (Kaggle) Airfoil self-noise (UCI)

Benchmarks: House Sales synthetic outliers Health indicators label screening Airfoil two-sample test synthetic outlier detection, label screening, and two-sample scenarios

Metrics: FDR power FWER (marginal and conditional) type I error (size) rejection proportion median p-value

Baselines: CP (unweighted conformal p-value with BH) THR (unweighted thresholding) CT (conformal test) DCT (de-biased conformal test)

Builds on: conformal prediction randomly localized conformal prediction weighted conformal p-values Benjamini-Hochberg procedure conditional calibration

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