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Boosting Methods for Interval-censored Data with Regression and Classification

ICLR 2025 · Learning theory and algorithms › Prediction and decision losses · approach: Data attribution and recourse · 1 citations (OpenAlex)

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Proposes L2Boost-CUT and L2Boost-IMP, nonparametric boosting methods that use censoring unbiased transformations and an ICRF survivor estimate to handle interval-censored responses for regression and classification.

Problem

Boosting assumes fully observed data, but interval-censored survival times (known only to lie in an interval) are common and existing boosting extensions mainly handle right censoring or missing responses.

Approach

Adjust the L2 loss via a censoring unbiased transformation (CUT) so its expectation matches the uncensored risk, estimate the conditional survivor function with interval-censored recursive forests, and run functional gradient L2 boosting with smoothing-spline base learners; a companion imputation variant (IMP) replaces the response with the CUT transform.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
replace the naive midpoint response with L2Boost-CUT or L2Boost-IMPinterval-censored survival-time prediction · synthetic lognormal AFT and loglogistic AFTSMaxAEHelped
replace the naive midpoint response with L2Boost-CUT or L2Boost-IMPinterval-censored survival-time prediction · synthetic lognormal AFT and loglogistic AFTSMSqEHelped
replace the naive midpoint response with L2Boost-CUT or L2Boost-IMPinterval-censored survival-time prediction · synthetic lognormal AFT and loglogistic AFTSKDTHelped
replace the naive midpoint response with L2Boost-CUT or L2Boost-IMPinterval-censored survival-status prediction · synthetic datasensitivityHelped
use L2Boost-CUT instead of L2Boost-IMPL2Boost for interval-censored data · synthetic survival-status predictionsensitivityNo clear effect
use L2Boost-CUT instead of L2Boost-IMPL2Boost for interval-censored data · synthetic survival-status predictionspecificityNo clear effect
use L2Boost-CUT instead of L2Boost-IMPL2Boost for interval-censored data · synthetic experimentsperformanceNo clear effect

Surprising findings

Limitations

Experimental setup

Datasets: synthetic AFT data (lognormal and loglogistic) Signal Tandmobiel data Bangkok HIV data

Benchmarks: synthetic AFT simulations Signal Tandmobiel Bangkok HIV

Metrics: SMaxAE SMSqE SKDT (sample Kendall's tau) sensitivity specificity

Baselines: oracle method (true phi) reference method (complete data) naive surrogate response (midpoint) COX model

Builds on: L2Boost L2WCBoost interval censored recursive forests censoring unbiased transformation

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