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AI-Researcher: Autonomous Scientific Innovation

NeurIPS 2025 · Large language models › AI and society · approach: Social-science view of AI evaluation · 3 citations (OpenAlex)

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Introduces AI-Researcher, a multi-agent system that automates literature review, idea generation, code implementation, and paper writing, and Scientist-Bench, a 22-paper benchmark for evaluating it with LLM judges.

Problem

Autonomous scientific research (idea-to-paper) lacks end-to-end systems and standardized benchmarks for measuring implementation success and research quality against human papers.

Approach

A multi-agent pipeline (Knowledge Acquisition, Resource Analyst, Idea Generator, Code Agent, Advisor Agent, Documentation Agent) with iterative advisor feedback and hierarchical manuscript writing, evaluated by pairwise LLM review against human-authored papers, using Level-1 (guided) and Level-2 (open-ended) tasks.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
use open-ended exploration without explicit research instructions rather than guided Level-1 tasksAI-Researcher · Scientist-Bench scientific paper evaluationAverage Rating: -0.58~-1.76 to -0.20~-1.01Helped
use open-ended exploration without explicit research instructions rather than guided Level-1 tasksAI-Researcher · Scientist-Bench scientific paper evaluationComparable(%): 15.79%~78.95% to 40.00%~100.00%Helped
use Claude-series instead of 4o-series as the research-agent backbone (ablation)AI-Researcher · Scientist-Bench evaluation subsetcompleteness: 50% -> 87.5%Helped
use Claude-series instead of 4o-series as the research-agent backbone (ablation)AI-Researcher · Scientist-Bench evaluation subsetcorrectness: 1.0 -> 2.75Helped
perform Level-2 novel-idea implementation instead of Level-1 adaptationAI-Researcher (Claude-series) · Scientist-Bench implementationcorrectness: 2.5 -> 2.25Hurt
use Claude-3.5 rather than GPT-4o as the research-agent backbone (ablation)AI-Researcher · Scientist-Bench backbone comparisonComparable(%): 71.43% -> 85.71% (GPT-4o reviewer); 42.86% -> 28.57% (o1-mini reviewer); 0.00% -> 14.29% (o3-mini reviewer); 0.00% -> 0.Mixed

Surprising findings

Limitations

Experimental setup

Datasets: Scientist-Bench (22 papers from 2022-2024 across diffusion models, vector quantization, GNNs, recommender systems) ICLR 2021-2023 accept/reject paper pairs (32 pairs)

Benchmarks: Scientist-Bench ICLR 2021-2023 accept/reject pairs

Metrics: completeness rate correctness score (1-5) mean pairwise rating (-3 to 3) comparable percentage (rating >= -1.0) selection accuracy

Baselines: AI Scientist Agent Laboratory CycleResearcher AI co-scientist

Builds on: AI Scientist Agent Laboratory MetaGPT AutoGen ResearchAgent

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