Research map / Label-efficient and robust learning / Knowledge distillation
A Knowledge Distillation-Based Approach to Enhance Transparency of Classifier Models
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Distills a DenseNet121 teacher into a five-layer CNN student via KD and visualizes layer-averaged feature maps for interpretability on three medical image datasets.
Problem
Deep CNNs used for medical image classification are large and opaque, so clinicians cannot easily understand their decision process; the paper asks how to build a simple, accurate, and interpretable classifier.
Approach
Use knowledge distillation from a DenseNet121 teacher to a shallow five-layer student CNN, then interpret the student by averaging feature maps per layer (KD-FMV), which yields faster explanations than Grad-CAM and SHAP on the teacher.
Key results
- Best student on brain tumor reaches 0.9748 test accuracy vs 0.9877 for the DenseNet121 teacher (table).
- Best eye-disease student reaches 0.9351 accuracy vs 0.9837 for the teacher, roughly a 5% drop.
- Student FLOPs are 232.70M vs 566.89M for the teacher, and SHAP mean execution time falls from about 67.7 s to about 15.6 s per image.
Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| distill DenseNet121 into the five-layer student CNN using α=0.7, T=10 | KD-FMV · Brain tumor test | accuracy: 0.9877 -> 0.9748 | Hurt |
| distill DenseNet121 into the five-layer student CNN using α=0.4, T=15 | KD-FMV · Eyes disease test | accuracy: 0.9837 -> 0.9351 | Hurt |
| distill DenseNet121 into the five-layer student CNN using α=0.4, T=5 | KD-FMV · Alzheimer test | accuracy: 0.9938 -> 0.9946 | Helped |
| vary α and T across the reported settings (ablation) | KD-FMV student · Brain tumor test | accuracy: 0.9572; 0.9656; 0.9748; 0.9702; 0.9748; 0.9717 | Mixed |
| vary α and T across the reported settings (ablation) | KD-FMV student · Eyes disease test | accuracy: 0.9074; 0.8750; 0.9351; 0.8958; 0.8680; 0.9219 | Mixed |
| vary α and T across the reported settings (ablation) | KD-FMV student · Alzheimer test | accuracy: 0.9946; 0.9906; 0.9928; 0.9934; 0.9915; 0.9919 | Mixed |
| use the five-layer student instead of the teacher for Grad-CAM analysis | KD-FMV · Brain tumor | Fidelity score (Avg): 0.9298 -> 0.9277 | Hurt |
| use the five-layer student instead of the teacher for Grad-CAM analysis | KD-FMV · Eyes disease | Fidelity score (Avg): 0.9059 -> 0.8630 | Hurt |
| use the five-layer student instead of the teacher for Grad-CAM analysis | KD-FMV · Alzheimer | Fidelity score (Avg): 0.9112 -> 0.9132 | Helped |
| use the five-layer student instead of the teacher for SHAP analysis | KD-FMV · Brain tumor | Fidelity score (Avg): 0.9404 -> 0.9277 | Hurt |
| use the five-layer student instead of the teacher for SHAP analysis | KD-FMV · Eyes disease | Fidelity score (Avg): 0.8700 -> 0.8630 | No clear effect |
| use the five-layer student instead of the teacher for SHAP analysis | KD-FMV · Alzheimer | Fidelity score (Avg): 0.9359 -> 0.9132 | Hurt |
Surprising findings
- On Alzheimer's data the student (0.9946 accuracy) slightly outperforms the teacher (0.9938).
- Grad-CAM/SHAP fidelity scores on the teacher are not uniformly higher than the proposed student-based explanations; the proposed method is lower on several classes.
Limitations
- Accuracy drops about 5% on the eye disease dataset, which the authors attribute to shallow networks.
- Interpretability is assessed largely qualitatively, and the fidelity metric as defined uses adversarial samples in a way that is weakly specified.
- The student's explanations are compared against teacher-based Grad-CAM and SHAP rather than clinician ground truth.
Experimental setup
Datasets: Brain tumor MRI dataset (figshare, SARTAJ, Br35H) Eye disease fundus dataset Alzheimer MRI dataset
Benchmarks: Brain tumor MRI dataset Eye disease fundus dataset Alzheimer MRI dataset
Metrics: accuracy F1 score loss fidelity score FLOPs mean execution time
Baselines: Grad-CAM SHAP DenseNet121
Builds on: knowledge distillation Grad-CAM SHAP
Closest papers by meaning
- Class Attention Transfer Based Knowledge Distillation (CVPR 2023 · similarity 0.86)
- VkD: Improving Knowledge Distillation using Orthogonal Projections (CVPR 2024 · similarity 0.85)
- Search to Distill: Pearls Are Everywhere but Not the Eyes (CVPR 2020 · similarity 0.85)
- Decoupled Knowledge Distillation (CVPR 2022 · similarity 0.85)
- MICA: Towards Explainable Skin Lesion Diagnosis via Multi-Level Image-Concept Alignment (AAAI 2024 · similarity 0.84)
- Debiased Distillation for Consistency Regularization (AAAI 2025 · similarity 0.83)
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