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A Knowledge Distillation-Based Approach to Enhance Transparency of Classifier Models

AAAI 2025 · Label-efficient and robust learning › Knowledge distillation · approach: Self and data-free distillation · 5 citations (OpenAlex)

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Distills a DenseNet121 teacher into a five-layer CNN student via KD and visualizes layer-averaged feature maps for interpretability on three medical image datasets.

Problem

Deep CNNs used for medical image classification are large and opaque, so clinicians cannot easily understand their decision process; the paper asks how to build a simple, accurate, and interpretable classifier.

Approach

Use knowledge distillation from a DenseNet121 teacher to a shallow five-layer student CNN, then interpret the student by averaging feature maps per layer (KD-FMV), which yields faster explanations than Grad-CAM and SHAP on the teacher.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
distill DenseNet121 into the five-layer student CNN using α=0.7, T=10KD-FMV · Brain tumor testaccuracy: 0.9877 -> 0.9748Hurt
distill DenseNet121 into the five-layer student CNN using α=0.4, T=15KD-FMV · Eyes disease testaccuracy: 0.9837 -> 0.9351Hurt
distill DenseNet121 into the five-layer student CNN using α=0.4, T=5KD-FMV · Alzheimer testaccuracy: 0.9938 -> 0.9946Helped
vary α and T across the reported settings (ablation)KD-FMV student · Brain tumor testaccuracy: 0.9572; 0.9656; 0.9748; 0.9702; 0.9748; 0.9717Mixed
vary α and T across the reported settings (ablation)KD-FMV student · Eyes disease testaccuracy: 0.9074; 0.8750; 0.9351; 0.8958; 0.8680; 0.9219Mixed
vary α and T across the reported settings (ablation)KD-FMV student · Alzheimer testaccuracy: 0.9946; 0.9906; 0.9928; 0.9934; 0.9915; 0.9919Mixed
use the five-layer student instead of the teacher for Grad-CAM analysisKD-FMV · Brain tumorFidelity score (Avg): 0.9298 -> 0.9277Hurt
use the five-layer student instead of the teacher for Grad-CAM analysisKD-FMV · Eyes diseaseFidelity score (Avg): 0.9059 -> 0.8630Hurt
use the five-layer student instead of the teacher for Grad-CAM analysisKD-FMV · AlzheimerFidelity score (Avg): 0.9112 -> 0.9132Helped
use the five-layer student instead of the teacher for SHAP analysisKD-FMV · Brain tumorFidelity score (Avg): 0.9404 -> 0.9277Hurt
use the five-layer student instead of the teacher for SHAP analysisKD-FMV · Eyes diseaseFidelity score (Avg): 0.8700 -> 0.8630No clear effect
use the five-layer student instead of the teacher for SHAP analysisKD-FMV · AlzheimerFidelity score (Avg): 0.9359 -> 0.9132Hurt

Surprising findings

Limitations

Experimental setup

Datasets: Brain tumor MRI dataset (figshare, SARTAJ, Br35H) Eye disease fundus dataset Alzheimer MRI dataset

Benchmarks: Brain tumor MRI dataset Eye disease fundus dataset Alzheimer MRI dataset

Metrics: accuracy F1 score loss fidelity score FLOPs mean execution time

Baselines: Grad-CAM SHAP DenseNet121

Builds on: knowledge distillation Grad-CAM SHAP

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