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A data and task-constrained mechanistic model of the mouse outer retina shows robustness to contrast variations

NeurIPS 2025 · Probabilistic and scientific modeling › Dynamical systems · approach: Synaptic plasticity learning rules · 0 citations (OpenAlex)

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Builds a data- and task-constrained mechanistic model of the mouse outer retina (photoreceptors, horizontal cells, bipolar cells) and shows it is robust to contrast variations.

Problem

How photoreceptors, horizontal cells, and bipolar cells together implement contrast-invariant coding of visual information in the mouse outer retina remains unclear.

Approach

A mechanistic model of the outer retina constrained by experimental data and by a visual task, used to examine how cell-type interactions yield robustness to contrast variations.

Key results

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