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Semi-supervised TEE Segmentation via Interacting with SAM Equipped with Noise-Resilient Prompting

AAAI 2024 · Label-efficient and robust learning › Semi-supervised learning · approach: Semi-supervised medical segmentation · 3 citations (OpenAlex)

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Proposes a semi-supervised LAA segmentation method for TEE images that uses SAM, prompted with noise-resilient points from a self-reconstruction teacher-student network, to refine pseudo labels, plus feature-level self-perturbation.

Problem

Semi-supervised left atrial appendage segmentation in transesophageal echocardiography (TEE) suffers from pseudo-label bias due to distribution mismatch between highly imbalanced labeled and unlabeled data, and from scarce annotations and noisy TEE images.

Approach

Incorporates the foundation model SAM into a teacher-student SSL framework: a self-reconstruction (denoising) module produces reconstructed images and candidate masks from which consensus high-confidence points serve as noise-resilient SAM prompts, and SAM outputs are adaptively fused with the teacher's predictions into pseudo labels; a self-perturbation module (SPFA) swaps encoder features betwee

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
add the SAM-powered pseudo label generator (GPL) (ablation)semi-supervised Unet · TEE dataset, 20% labeledDice: 0.8293 -> 0.8469Helped
add the SAM-powered pseudo label generator (GPL) (ablation)semi-supervised Unet · TEE dataset, 20% labeledASD: 2.08 -> 1.92Helped
add SPFA (ablation)semi-supervised Unet · TEE dataset, 20% labeledDice: 0.8293 -> 0.8366Helped
add SPFA (ablation)semi-supervised Unet · TEE dataset, 20% labeledASD: 2.08 -> 1.94Helped
add the self-reconstruction mechanism (SRM) for prompts and reconstructed inputs (ablation)SAM-powered semi-supervised Unet · TEE dataset, 20% labeledDice: 0.8249 -> 0.8604Helped
add the self-reconstruction mechanism (SRM) for prompts and reconstructed inputs (ablation)SAM-powered semi-supervised Unet · TEE dataset, 20% labeledASD: 2.16 -> 1.65Helped
use SPFA instead of DA (ablation)GPL-based semi-supervised Unet · TEE dataset, 20% labeledDice: 0.8385 -> 0.8604Helped
use SPFA instead of DA (ablation)GPL-based semi-supervised Unet · TEE dataset, 20% labeledASD: 1.97 -> 1.65Helped
use SPFA instead of FA dropout (ablation)GPL-based semi-supervised Unet · TEE dataset, 20% labeledDice: 0.8404 -> 0.8604Helped
use SPFA instead of FA dropout (ablation)GPL-based semi-supervised Unet · TEE dataset, 20% labeledASD: 1.84 -> 1.65Helped

Surprising findings

Limitations

Experimental setup

Datasets: in-house TEE dataset (100 patients)

Benchmarks: in-house TEE LAA dataset

Metrics: Dice ASD

Baselines: Unet ST++ UniMatch MCF BCP UCMT

Builds on: Mean Teacher Neighbor2Neighbor Segment Anything UniMatch ST++

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