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GMAI-MMBench: A Comprehensive Multimodal Evaluation Benchmark Towards General Medical AI
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Introduces GMAI-MMBench, a 26K-question VQA benchmark built from 284 medical datasets across 38 modalities, organized in a lexical tree by task, department, and perceptual granularity, and evaluates 50 LVLMs zero-shot.
Problem
Existing medical multimodal benchmarks are narrow in modality/task, built from literature-derived image-text pairs, lack clinical relevance, and are not categorized well enough for customized evaluation across clinical tasks, departments, and perceptual granularities.
Approach
Converts curated clinical image-label datasets (public and hospital) into VQA items using a lexical tree that tags each item by modality, clinical VQA task, department, and perceptual granularity (image, box, mask, contour), enabling customized subset evaluation.
Key results
- GPT-4o achieves the best overall test accuracy of 53.96% on GMAI-MMBench, while the random baseline is 25.94%.
- Open-source MedDr (43.69%) and DeepSeek-VL-7B (43.43%) approach proprietary GPT-4V (44.08%) and surpass Claude3-Opus (32.44%) and Qwen-VL-Max (42.16%) on overall test accuracy.
- Box-level perception is consistently the worst granularity, even below image-level, indicating LVLM sensitivity to bounding-box prompts.
Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| use box-level rather than image-level perception | LVLMs · GMAI-MMBench single-choice questions | accuracy | Hurt |
| fine-tune LLaVA-V1.5-7B for medical tasks as LLaVA-Med | LLaVA-V1.5-7B · GMAI-MMBench overall test | accuracy: 37.96 -> 19.60 | Hurt |
| build medical instruction-tuning data from high-quality medical image classification datasets | MedDr · GMAI-MMBench overall test | accuracy | Helped |
Surprising findings
- Box-level annotation yields worse accuracy than unannotated image-level questions across models.
- Most medical-specific models underperform general LVLMs; LLaVA-Med scores below LLaVA-V1.5-7B.
Limitations
- Manual curation may introduce biases and focuses only on medical subjects, which may not fully capture general medical AI.
- Evaluation is zero-shot only and does not include human expert comparison (planned future work).
Experimental setup
Datasets: 284 medical image datasets (public and hospital-shared)
Benchmarks: GMAI-MMBench
Metrics: accuracy macro-averaged accuracy multi-choice accuracy (ACC_mcq) recall (Recall_mcq)
Baselines: GPT-4o GPT-4V Gemini 1.5 Gemini 1.0 Claude3-Opus Qwen-VL-Max MedDr LLaVA-Med Med-Flamingo RadFM Qilin-Med-VL-Chat DeepSeek-VL-7B
Builds on: SA-Med2D-20M protocol VLMEvalKit
Closest papers by meaning
- GMAI-VL & GMAI-VL-5.5M: A Large Vision-Language Model and a Comprehensive Multimodal Dataset Towards General Medical AI (AAAI 2026 · similarity 0.94)
- OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM (CVPR 2024 · similarity 0.91)
- How Do Medical MLLMs Fail? A Study on Visual Grounding in Medical Images (ICLR 2026 · similarity 0.90)
- MediConfusion: Can you trust your AI radiologist? Probing the reliability of multimodal medical foundation models (ICLR 2025 · similarity 0.90)
- Toward a Vision-Language Foundation Model for Medical Data: Multimodal Dataset and Benchmarks for Vietnamese PET/CT Report Generation (NeurIPS 2025 · similarity 0.89)
- Beyond Classification Accuracy: Neural-MedBench and the Need for Deeper Reasoning Benchmarks (ICLR 2026 · similarity 0.89)
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