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Hamiltonian Monte Carlo using an adjoint-differentiated Laplace approximation: Bayesian inference for latent Gaussian models and beyond

NeurIPS 2020 · Probabilistic and scientific modeling › Variational and generative sampling · approach: Stochastic gradient MCMC · 9 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use adjoint method with a single reverse sweep instead of forward-mode dK/dphiLaplace marginal gradient · SKIM, p=200wall time per differentiation (s): 1.47 s -> 0.009 sHelped
Marginalize latent Gaussian with embedded Laplace approximationDynamic HMC · Prostate cancer horseshoe regressiondivergent transitions: 13 -> 0Helped
Marginalize latent Gaussian with embedded Laplace approximationDynamic HMC · SKIM, 200 covariates, delta_a=0.8divergent transitions: 36 -> 0Helped
Marginalize latent Gaussian with embedded Laplace approximationDynamic HMC · SKIM, full prostate dataestimated run time (hours): ~20 hours -> ~10 hoursHelped
Marginalize latent Gaussian with embedded Laplace approximationDynamic HMC · Disease map GPwarmup time (s): ~200 seconds -> ~10 secondsHelped
Use analytical cotangent w in the adjoint method (ablation)Adjoint differentiation · SKIMdifferentiation speedHelped
Raise delta_a from 0.8 to 0.99 for full HMC (ablation)Full HMC · SKIM, 200 covariatesdivergent transitions: 36 -> 0Helped
Raise delta_a from 0.8 to 0.99 for full HMC (ablation)Full HMC (non-centered) · Prostate horseshoe regressiondivergent transitions: ~150 -> 186Hurt

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