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Approximate Bayesian Inference for a Mechanistic Model of Vesicle Release at a Ribbon Synapse

NeurIPS 2019 · Probabilistic and scientific modeling › Uncertainty and Gaussian processes · approach: Simulation-based inference · 18 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
use mechanistic LNR release model instead of GLMvesicle release prediction · zebrafish bipolar cell recordingsdiscrepancy / multivesicular event captureHelped
add discrete vesicle-release stage (beta-binomial multivesicular release) to LN modelLN model · zebrafish bipolar cell recordingsmatch to temporal precision of large eventsHelped
fit model to experimental instead of synthetic dataLNR with ABC · discrepancy among tracesdiscrepancyHurt

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