Research map / Probabilistic and scientific modeling / Molecules and proteins
Disease Trajectory Maps
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Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| use DTM representations instead of LMM | scleroderma trajectory representation · PFVC, pulmonary arterial hypertension | p-value: 0.013 -> 0.002 | Helped |
| use DTM representations instead of LMM/FPCA | representation association test · TSS, ulcers and gangrene | p-value: 0.573 -> 0.009 | Helped |
| use DTM instead of FPCA | representation association test · PFVC, pulmonary hypertension | p-value: 0.000 -> 0.000 | No clear effect |
| use DTM instead of LMM | representation association test · PFVC, pulmonary hypertension | p-value: 0.270 -> 0.000 | Helped |
| use DTM instead of LMM | representation association test · PFVC, myositis | p-value: 0.337 -> 0.004 | Helped |
| use DTM instead of LMM | representation association test · TSS, gastrointestinal complications | p-value: 0.026 -> 0.011 | Helped |
| use DTM instead of LMM | representation association test · PFVC, congestive heart failure | p-value: 0.170 -> 0.013 | Helped |
| use DTM instead of LMM | representation association test · PFVC, gastrointestinal complications | p-value: 0.328 -> 0.347 | Hurt |
| use DTM instead of LMM | held-out likelihood · PFVC | Subject log-likelihood: -17.59 -> -17.74 | No clear effect |
| use DTM instead of LMM | held-out likelihood · TSS | Observation log-likelihood: -3.47 -> -3.32 | Helped |
| use DTM instead of FPCA | held-out likelihood · PFVC | Observation log-likelihood: -4.03 -> -3.98 | Helped |
| use DTM instead of LMM | interstitial lung disease association · PFVC and TSS | p-value: 0.000 -> 0.000 | No clear effect |
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