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Extracting Rare Dependence Patterns via Adaptive Sample Reweighting

ICML 2025 · Probabilistic and scientific modeling › Causal discovery · approach: Identifiability with hidden confounders

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Proposes RHSIC/RKCIT, kernel (conditional) independence tests that learn adaptive sample importance weights to amplify rare dependence, and integrates them into the PC algorithm (RD-PC) for causal discovery.

Problem

Existing independence and conditional independence tests miss dependence that is significant only within small regions of the data distribution ("rare dependence"), causing false negatives that propagate errors in causal discovery.

Approach

Learn a non-negative sample reweighting function (in an RKHS, with normalization and regularization) by maximizing a reweighted HSIC/conditional HSIC on a training split, then test independence on the held-out split with the reweighted statistic and a permutation test, and plug the test into PC.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Apply adaptive sample importance reweighting instead of using the original HSIC testHSIC independence testing · Sachs dataset (PKA, PJINK)p-value: 0.601 -> 0.004Helped
Apply adaptive sample importance reweighting using the federal funds rate as referenceHSIC independence testing · Monthly JPY/USD exchange rates and U.S. federal funds rates (1990–2010)p-value: 0.2174 -> 0.0005Helped
Use adaptive sample importance reweighting to detect rare dependenceIndependence tests · Synthetic Data Generation I and IIpowerHelped
Use adaptive sample importance reweighting for conditional independence testingKCIT · Synthetic conditional independence testspower: 50% betterHelped

Surprising findings

Limitations

Experimental setup

Datasets: Sachs flow cytometry dataset FRED JPY/USD exchange rate and federal funds rate data synthetic data (DG I, DG II, CI generators)

Benchmarks: Synthetic DG I and DG II independence tests Synthetic CI tests Sachs dataset FRED exchange rate and federal funds dataset

Metrics: Type I error rate power p-value

Baselines: HSIC RDC FHSIC FisherScan LFHSIC KCIT RCIT CCIT

Builds on: HSIC KCIT PC algorithm RCIT

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