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SiBBlInGS: Similarity-driven Building-Block Inference using Graphs across States
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Proposes SiBBlInGS, a graph-regularized dictionary learning framework that extracts sparse building blocks and their per-trial temporal traces across multiple states, with cross-state similarity controlled by a state graph and channel graphs.
Problem
Identifying interpretable, sparse building blocks from multi-state, multi-trial time-series data where trials vary in duration, sampling, and missing samples, and where building-block composition may adapt subtly across states.
Approach
Extends re-weighted l1 graph filtering dictionary learning with channel-similarity graphs (per state) and a state-similarity graph P that regularizes building-block matrices across states, with per-BB weights nu allowing both state-invariant and state-specific BBs; trial temporal traces are updated independently per trial.
Key results
- On synthetic data (N=100, p=10, D=3), SiBBlInGS recovers ground-truth building blocks and traces with correlations close to one and outperforms listed baselines.
- On the monkey reaching data, all identified BBs show within/between state correlation ratio greater than 1, and multi-class logistic regression on the traces accurately predicts the reach direction state.
- On Google Trends, the identified BBs recover meaningful clusters (college, Passover, winter, COVID) with state-specific temporal patterns, and other methods with p=5 produced less meaningful BBs (qualitative).
Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| use SiBBlInGS instead of the compared tensor-factorization, PCA, and regression baselines | synthetic data · synthetic data | ground-truth BB recovery | Helped |
| use SiBBlInGS instead of other methods with the same number of BBs | Google Trends analysis · Google Trends | interpretability of BB clusters | Helped |
| apply SiBBlInGS to EEG recordings | EEG analysis · pre-seizure EEG | detection of localized pre-seizure activity | Helped |
| infer temporal traces with SiBBlInGS | SiBBlInGS · monkey reaching-task neural recordings | within-state versus between-state temporal correlation ratio: >1 | Helped |
Surprising findings
- Hopkins shows a less pronounced COVID-related search peak in Maryland, where the university and hospital are located, attributed to local familiarity.
Limitations
- Assumes Gaussian noise statistics whereas Poisson may be more suitable
- Linear mapping from building blocks to observations
- Does not handle missing channels or cross-trial channel identity changes, nor directional connectivity
Experimental setup
Datasets: synthetic data Google Trends monkey somatosensory cortex reaching task recordings EEG recordings of epileptic patient
Benchmarks: synthetic data ground truth recovery Google Trends monkey somatosensory reaching data epilepsy EEG
Metrics: Jaccard index correlation with ground truth within/between state correlation ratio logistic regression state prediction accuracy
Baselines: PARAFAC Tucker decomposition PCA (global and local) sparse PCA NONFAT NNDTN mTDR dPCA
Builds on: re-weighted l1 graph filtering (RWL1-GF) dictionary learning PARAFAC demixed PCA targeted dimensionality reduction
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