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InfoNet: Neural Estimation of Mutual Information without Test-Time Optimization

ICML 2024 · Probabilistic and scientific modeling › Molecules and proteins · approach: Sparse concepts and hypothesis testing · 0 citations (OpenAlex)

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Proposes InfoNet, an attention-based network trained on simulated GMM data to directly output a discretized optimal Donsker-Varadhan discriminant, giving mutual information estimates without test-time optimization.

Problem

Estimating mutual information from sample sequences is slow for real-time use when neural estimators like MINE must be re-optimized for each new distribution, and histogram-based methods are not differentiable.

Approach

Train an attention-based network on many simulated GMM joint distributions so it predicts the optimal Donsker-Varadhan discriminant as a 2D lookup table in a single feed-forward pass, with a copula (empirical CDF) preprocessing step; MI is then obtained by summing over the table.

Key results

Measured effects reported in the paper

What was changedWhereMeasuredEffect
Replace test-time optimization with InfoNet feed-forward estimationMI estimation on GMM distributions · GMM, sequence lengths 200–5000runtime: 0.821 -> 0.010 (sequence length 200); 1.235 -> 0.003 (sequence length 5000)Helped
Use InfoNet instead of MINE-500MI estimation on multi-component GMMs · GMM, MI bins 0.0–0.9mean error: -0.058 -> 0.004 (MI 0.1); -0.485 -> -0.138 (MI 0.9)Helped
Use InfoNet instead of MINECorrelation-order prediction · GMM, K=1–10order accuracy: 98.5 -> 99.8 (K=1); 78.1 -> 99.5 (K=10)Helped
Add a Gaussian smoothing kernel to the lookup table (ablation)InfoNet lookup table · Lookup-table visualizationsmoothnessHelped

Surprising findings

Limitations

Experimental setup

Datasets: Synthetic Gaussian mixture model (GMM) distributions PointOdyssey

Benchmarks: Gaussian sanity check GMM multi-component MI error correlation order accuracy high-dimensional independence testing PointOdyssey motion segmentation

Metrics: runtime (seconds) mean error error variance order accuracy (%) AUC of ROC precision-recall

Baselines: KSG KDE MINE Energy Distance

Builds on: MINE Donsker-Varadhan representation sliced mutual information Kraskov-Stoegbauer-Grassberger (KSG) estimator

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