Research map / Probabilistic and scientific modeling / Molecules and proteins
MAGAN: Aligning Biological Manifolds
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Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| Add correspondence loss to align mapped points with their original representations (ablation) | GAN manifold mapping · CyTOF panels (held-out CD3) | correlation: -.275 -> .801 | Helped |
| Add correspondence loss (ablation) | MAGAN mapping between CyTOF and scRNA-seq · Paired CyTOF and scRNA-seq | MSE(x1, G21(x2)): 99.3 -> 22.0 | Helped |
| Add correspondence loss (ablation) | MAGAN mapping between CyTOF and scRNA-seq · Paired CyTOF and scRNA-seq | MSE(x2, G12(x1)): 33.7 -> 7.1 | Helped |
| Add one labeled pair through semi-supervised correspondence loss (ablation) | MAGAN · MNIST 3s and 7s with 120-degree-rotated images | correct manifold alignment | Helped |
| Add correspondence loss across shared markers (ablation) | MAGAN · CyTOF panels (cross-validation over shared markers) | correlation | Helped |
| Add correspondence loss to preserve pointwise subpopulation relationships (ablation) | GAN mapping between CyTOF replicates · CyTOF replicates | subpopulation correspondence | Helped |
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