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Adversarial Time-to-Event Modeling

ICML 2018 · Probabilistic and scientific modeling › Molecules and proteins · approach: Survival analysis under censoring · 24 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
use adversarial DATE rather than parametric log-normal AFT DRAFTDATE · EHR non-censored test setmedian relative absolute error: 36.7 -> 23.6Helped
use adversarial DATE rather than parametric log-normal AFT DRAFTDATE · flchain non-censored test setmedian relative absolute error: 26.2 -> 19.5Helped
use adversarial DATE rather than parametric log-normal AFT DRAFTDATE · support non-censored test setmedian relative absolute error: 2.0 -> 2.7Hurt
use adversarial DATE rather than parametric log-normal AFT DRAFTDATE · seer non-censored test setmedian relative absolute error: 23.7 -> 18.6Helped
use an adversarial autoencoder for covariates rather than imputing missing covariates (ablation)DATE · EHR, flchain, support, and seer non-censored test setsmedian relative absolute error: EHR 23.6 -> 24.5; flchain 19.5 -> 19.3; support 2.7 -> 1.5; seer 18.6 -> 20.2Mixed
add stochastic noise to all generator layers instead of using input-layer noise only (ablation)DATE · support non-censored test-set distributionsmedian 95% interval width: 22.4 -> 149.9Helped
add stochastic noise to all generator layers instead of using input-layer noise only (ablation)DATE · support censored test-set distributionsmedian 95% interval width: 86.9 -> 1397.3Helped
use Uniform(0,1) noise rather than Uniform(-1,1) noise on all generator layers (ablation)DATE · support non-censored test-set distributionsmedian 95% interval width: 60.0 -> 149.9Helped
use Uniform(0,1) noise rather than Gaussian(0,1) noise on all generator layers (ablation)DATE · support non-censored test-set distributionsmedian 95% interval width: 37.9 -> 149.9Helped
add an ordering cost function to the DATE objective (ablation)DATE · time-to-event orderingconcordance indexNo clear effect
extend DRAFT to a mixture of log-normal distributions with different variances but shared mean (ablation)DRAFT · time-to-event predictionrelative absolute errorNo clear effect

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