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Exploring the Interaction between Local and Global Latent Configurations for Clustering Single-Cell RNA-Seq: A Unified Perspective
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Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| Add the FR filtering mechanism and FD correction mechanism (ablation) | scTPF · Muraro, Plasschaert, and Young | ACC: 91.94 -> 95.76; 93.88 -> 97.46; 81.49 -> 84.48 | Helped |
| Add the FD correction mechanism (ablation) | scTPF with FR filtering · Muraro, Plasschaert, and Young | ACC: 93.78 -> 95.76; 97.09 -> 97.46; 82.04 -> 84.48 | Helped |
| Add the FR filtering mechanism (ablation) | scTPF with FD correction · Muraro, Plasschaert, and Young | ACC: 94.44 -> 95.76; 97.30 -> 97.46; 83.57 -> 84.48 | Helped |
| Combine probability-based F1 and topology-based F2 filtering (ablation) | scTPF · Muraro, Plasschaert, QX LM, and Young | ACC: 93.59 -> 95.76; 96.99 -> 97.46; 99.60 -> 99.71; 79.19 -> 84.48 | Helped |
| Combine global content correction T1 and local topology correction T2 (ablation) | scTPF · Muraro, Plasschaert, QX LM, and Young | ACC: 94.53 -> 95.76; 97.28 -> 97.46; 99.64 -> 99.71; 83.92 -> 84.48 | Helped |
| Use scTPF rather than scTAG | scRNA-seq clustering · Eight datasets (average) | NMI: 85.02 -> 92.93 | Helped |
| Use scTPF rather than scTAG | scRNA-seq clustering · Eight datasets (average) | ARI: 87.34 -> 94.06 | Helped |
Closest papers by meaning
- Clustering by Denoising: Latent plug-and-play diffusion for single-cell embeddings (ICLR 2026 · similarity 0.91)
- Unsupervised Gene-Cell Collective Representation Learning with Optimal Transport (AAAI 2024 · similarity 0.88)
- A Simple and Comprehensive Benchmark for Single-Cell Transcriptomics (AAAI 2025 · similarity 0.85)
- Enforcing Latent Euclidean Geometry in Single-Cell VAEs for Manifold Interpolation (ICML 2025 · similarity 0.85)
- A Unified Framework for Variable Selection in Model-Based Clustering with Missing Not at Random (NeurIPS 2025 · similarity 0.85)
- Semi-supervised Knowledge Transfer Across Multi-omic Single-cell Data (NeurIPS 2024 · similarity 0.84)
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