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Adaptive Instrument Design for Indirect Experiments
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Proposes DIA, an adaptive instrument-allocation method for indirect experiments that uses influence functions for leave-one-out MSE control variates and multi-rejection sampling to optimize a data collection policy over instruments for estimating non-linear IV/CATE estimators.
Problem
Sample-efficient estimation of treatment effects in indirect experiments, where treatment is only encouraged via instrumental variables, and instrument allocation is chosen without adaptive design, especially with many instruments and non-linear estimators.
Approach
Gradient-based search over a data-collection policy over instruments, with variance reduction via influence-function estimates of leave-one-out MSE (control variates computed without retraining) and multi-rejection sampling to reuse historical data under a new policy without exponential importance-weight variance.
Key results
- DIA improves the base estimator's accuracy by a factor of 1.2x to 10x over uniform allocation across domains.
- For some target accuracies, DIA needs only 80% to an order-of-magnitude less sample data than uniform.
- Gains show a U-shaped trend with number of instruments: largest potential gains with many instruments but harder policy learning when instruments are very numerous.
Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| adaptively allocate instruments with DIA instead of uniform allocation | 2SLS indirect experiment design · IV | MSE: 1.2× to 10× | Helped |
| adaptively allocate instruments with DIA instead of uniform allocation | Logistic regression conditional IV estimation · Conditional IV | MSE: 1.2× to 10× | Helped |
| adaptively allocate instruments with DIA instead of uniform allocation | Neural network IV estimation · TripAdvisor | MSE: 1.2× to 10× | Helped |
| use an RCT adaptive-design strategy naively for indirect experiments instead of DIA | Indirect experiment design · Indirect experiments | MSE | Hurt |
| increase the number of policy re-allocations (ablation) | DIA · IV, Conditional IV, and TripAdvisor | MSE | Helped |
| vary the number of available instruments (ablation) | DIA · IV, Conditional IV, and TripAdvisor | MSE | Mixed |
| change the rejection-sampling dataset size k (ablation) | Multi-rejection sampling policy evaluation · Policy MSE ordering | MSE | No clear effect |
Surprising findings
- Naively applying RL-style adaptive experiment design from direct experiments can perform worse than uniform sampling in indirect experiments.
Limitations
- Experiments restricted to relatively small synthetic and semi-synthetic settings
- Assumes homogeneous treatment effects (conditional LATE equals CATE)
- Does not yet handle natural-language or high-dimensional instruments
Experimental setup
Datasets: TripAdvisor customer data (simulator)
Benchmarks: IV simulator conditional IV simulator TripAdvisor simulator
Metrics: relative MSE versus uniform allocation
Baselines: uniform instrument allocation oracle brute-force search (IV setting) naive REINFORCE gradient importance sampling
Builds on: DeepIV two-stage least squares REINFORCE influence functions
Closest papers by meaning
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- Fast Proxy Experiment Design for Causal Effect Identification (NeurIPS 2024 · similarity 0.86)
- Targeted Sequential Indirect Experiment Design (NeurIPS 2024 · similarity 0.85)
- Data-Driven Selection of Instrumental Variables for Additive Nonlinear, Constant Effects Models (ICML 2025 · similarity 0.85)
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