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Constrained Submodular Optimization for Vaccine Design

AAAI 2023 · Learning theory and algorithms › Submodular and game algorithms · approach: Streaming submodular algorithms · 3 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use Optivax-P instead of random peptide selectionPeptide vaccine selection · 2,000 randomly generated settingsobjective scoreHelped
Use Optivax-P instead of linear approximationPeptide vaccine selection · 2,000 randomly generated settingsobjective scoreHelped
Select peptides with Optivax-P using the diminishing-returns objectiveSARS-CoV-2 vaccine design · SARS-CoV-2 vaccine designU5 objectiveHelped
Optimize with Optivax-P's diminishing-returns objective rather than previous design approaches19-peptide vaccine designs · SARS-CoV-2 vaccine design, n-times coverage evaluationn-times coverageMixed

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