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Interventional Bag Multi-Instance Learning on Whole-Slide Pathological Images

CVPR 2023 · Label-efficient and robust learning › Recognition and long-tail · approach: Partial and multi-label learning · 138 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Add IBMIL backdoor adjustmentTransMIL with CTransPath SRCL · Camelyon16AUC: 95.88 -> 97.00Helped
Add IBMIL backdoor adjustmentDSMIL with CTransPath SRCL · TCGA-NSCLCAUC: 97.13 -> 97.51Helped
Freeze confounders instead of learning them end-to-end (ablation)IBMIL with ResNet-18 + ABMIL · TCGA-NSCLCaccuracy: 83.81 -> 85.24Helped
Learn confounders end-to-end instead of freezing them (ablation)IBMIL with ResNet-18 + ABMIL · TCGA-NSCLCaccuracy: 85.24 -> 83.81Hurt
Concatenate bag and confounder features rather than combine them by element-wise addition (ablation)IBMIL with ResNet-18 + ABMIL · TCGA-NSCLCaccuracy: 84.76 -> 85.24Helped
Concatenate bag and confounder features rather than subtract them element-wise (ablation)IBMIL with ResNet-18 + ABMIL · TCGA-NSCLCaccuracy: 84.29 -> 85.24Helped
Use non-parametric mean pooling to generate bag features instead of the trained aggregator (ablation)IBMIL · TCGA-NSCLCAUC: 80.68 -> 89.14Mixed
Use non-parametric max pooling to generate bag features instead of the trained aggregator (ablation)IBMIL · TCGA-NSCLCAUC: 82.23 -> 84.95Mixed
Vary the confounder dictionary size K (ablation)IBMIL · TCGA-NSCLCperformanceNo clear effect
Increase joint feature-space dimension (ablation)IBMIL · TCGA-NSCLCperformanceMixed
Use class-specific rather than class-agnostic K-means to construct confounders (ablation)IBMIL · TCGA-NSCLCperformanceNo clear effect
Train baseline methods for additional epochs instead of adding interventional training (ablation)MIL baseline methods · WSI classificationperformanceHurt

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