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Benchmarking Self-Supervised Learning on Diverse Pathology Datasets

CVPR 2023 · Label-efficient and robust learning › Self-supervised and contrastive · approach: Data-efficient and robust self-supervision · 179 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use domain-aligned TCGA SSL pre-training instead of ImageNet-supervised pre-trainingPathology classification and nuclei segmentation · BACH, CRC, PCam, MHIST, CoNSePTop-1 accuracy or mPQHelped
Add pathology data from TULIP to TCGA pre-trainingMoCo · BACH, CRC, PCam, MHIST, CoNSeP linear evaluationTop-1 accuracy or mPQ: 80.83 -> 85.00; 90.93 -> 93.94; 80.79 -> 86.53; 76.25 -> 82.29; 33.49 -> 41.40Mixed
Use both 20x and 40x magnifications rather than one magnification (ablation)Pathology SSL pre-training · BACH, CRC, PCam, MHIST, CoNSeP fine-tuningTop-1 accuracy or mPQMixed
Add random vertical flips and remove solarization (ablation)BT pre-training · CoNSePmPQ: 50.71 -> 51.07Helped
Use RandStainNA or RandStainNA GMM instead of HED-light (ablation)BT pre-training · CoNSePmPQ: 50.48; 50.86; 50.71Helped
Add random grayscale to RandStainNA GMM (ablation)BT pre-training · CoNSePmPQ: 50.99 -> 51.13Helped
Use strong rather than weak color jitter with stain augmentation (ablation)BT pre-training · CoNSePmPQ: 51.13 -> 50.27; 51.61 -> 50.51Hurt
Use RandStainNA GMM, grayscale, and weak color jitter (ablation)BT pre-training · CoNSePmPQ: 50.99 -> 51.61Helped
Increase pre-training from 200 to 800 epochs (ablation)MoCo, SwAV, and BT · CoNSePmPQ: 51.16 -> 52.39Mixed
Increase ViT input size from 224 to 272 (ablation)DINO · CoNSePmPQ: 32.54 -> 35.81; 38.43 -> 41.13; 42.71 -> 40.08; 46.70 -> 44.24Mixed

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