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Dual-Stream Multiple Instance Learning Network for Whole Slide Image Classification With Self-Supervised Contrastive Learning

CVPR 2021 · Label-efficient and robust learning › Self-supervised and contrastive · approach: Contrastive versus non-contrastive theory · 888 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use the dual-stream aggregator instead of ABMILDSMIL · Camelyon16accuracy: 0.8450 -> 0.8682Helped
Use the dual-stream aggregator instead of ABMILDSMIL · Camelyon16FROC: 0.4056 -> 0.4296Helped
Add multiscale attention to DSMIL (ablation)DSMIL · Camelyon16accuracy: 0.8682 -> 0.8992Helped
Use self-supervised contrastive features instead of ImageNet features (ablation)DSMIL with fixed aggregator · Camelyon16accuracy: 0.6202 -> 0.8682Helped
Use self-supervised contrastive features instead of max-pooling-trained features (ablation)DSMIL with fixed aggregator · Camelyon16accuracy: 0.7099 -> 0.8682Helped
Use self-supervised contrastive features instead of patch-based features (ablation)DSMIL with fixed aggregator · Camelyon16accuracy: 0.6977 -> 0.8682Helped
Use self-supervised contrastive features instead of max-pooling-trained features (ablation)DSMIL with fixed aggregator · TCGA lung canceraccuracy: 0.7714 -> 0.9190Helped
Replace pyramidal multiscale fusion with single-scale 20× features (ablation)DSMIL · Camelyon16accuracy: 0.8682 -> 0.8992Hurt
Replace pyramidal fusion with concatenation (ablation)DSMIL · Camelyon16accuracy: 0.8682 -> 0.8992Hurt
Replace pyramidal fusion with max pooling across scales (ablation)DSMIL · Camelyon16accuracy: 0.8604 -> 0.8992Hurt
Mix instances from different magnifications in one bag (ablation)DSMIL · Camelyon16accuracy: 0.8837 -> 0.8992Hurt
Add the 1.25× scale to the 5× + 20× fusion (ablation)DSMIL · Camelyon16accuracy: 0.8992 -> 0.8760Hurt

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