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PANTHER: Pathway Augmented Nonnegative Tensor Factorization for HighER-order Feature Learning

AAAI 2021 · Probabilistic and scientific modeling › Molecules and proteins · approach: Generative latent models for single-cell data · 8 citations (OpenAlex)

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Measured effects reported in the paper

What was changedWhereMeasuredEffect
Use PANTHER instead of TASTETCGA cancer type classification · TCGA cancer type test setaccuracy: 0.8369 -> 0.8644Helped
Use PANTHER instead of LogParhypertension subtype classification · Hypertension test setaccuracy: 0.6532 -> 0.6888Helped
Use PANTHER instead of TASTEhypertension subtype classification · Hypertension test setaccuracy: 0.6532 -> 0.6888Helped
Concatenate pathway counts with gene countsNMF for TCGA cancer type classification · TCGA cancer type test setaccuracy: 0.8173 -> 0.7957Hurt
Concatenate pathway counts with gene countspenalized logistic regression for TCGA cancer type classification · TCGA cancer type test setaccuracy: 0.8016 -> 0.7682Hurt
Concatenate pathway counts with gene countspenalized logistic regression for hypertension classification · Hypertension test setaccuracy: 0.5938 -> 0.5819Hurt
Concatenate pathway counts with gene countsNMF for hypertension classification · Hypertension test setaccuracy: 0.6390 -> 0.6318Hurt

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