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Rescind: Countering Image Misconduct in Biomedical Publications with Vision-Language and State-Space Modeling

AAAI 2026 · Vision-language and multimodal › Multimodal LLMs · approach: Multimodal LLM benchmarks

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Builds Rescind, a ~600K-image biomedical forgery benchmark generated with VLM-guided diffusion and LLaVA-Med verification, and Integscan, a state-space vision-language model for forgery localization.

Problem

Detecting and localizing manipulated images (duplication, splicing, removal) in biomedical publications, where existing forensic datasets are small, modality-limited, and use simplistic synthetic manipulations.

Approach

Generate semantically controlled biomedical forgeries by combining MedSAM masks, BiomedCLIP-derived prompts, and Stable Diffusion inpainting with a LLaVA-Med verification loop, and detect them with Integscan, a Mamba-style linear-attention SSM encoder with prompt-conditioned fusion (IntegBoost, Integration modules).

Key results

Surprising findings

Limitations

Experimental setup

Datasets: BioFors Rescind-P Rescind-T M3D-Synth

Benchmarks: Rescind-T BioFors

Metrics: MCC F1 IoU precision recall NIQE PIQE SSIM LPIPS

Baselines: DF-ZM DF-PCT DF-FMT BusterNet ManTra-Net TruFor MONet SIFT

Builds on: BioFors Mamba MedSAM BiomedCLIP LLaVA-Med Stable Diffusion inpainting

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