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Prompt-SID: Learning Structural Representation Prompt via Latent Diffusion for Single Image Denoising
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Proposes Prompt-SID, a self-supervised single-image denoiser that uses a latent-diffusion-generated structural representation as a prompt fused into a transformer denoiser via a structural attention module, trained on downsampled sub-image pairs with a scale replay mechanism.
Problem
Self-supervised single-image denoising via blind-spot networks or sub-image downsampling loses pixel information and destroys structural detail, and the scale gap between downsampled training images and original-resolution test images hurts performance.
Approach
A latent diffusion model (RG-Diff) generates a structural representation of the original-scale image conditioned on the sub-image representation; this representation is injected into a transformer denoiser through a structural attention module, and a scale replay branch without gradients enforces consistency at original scale.
Key results
- On SIDD validation, Prompt-SID achieves 51.55 dB / 0.992 vs. B2U 51.36 dB and NBR2NBR 51.06 dB (raw-RGB).
- On Set14 with sigma in [5,50] Gaussian noise, Prompt-SID reports 31.22 dB, 0.32 dB above the N2C baseline's 31.41? (table shows Ours 31.22 vs baseline 31.41, so the 0.32 dB claim is not consistent with the table).
- Ablation on SIDD: removing RG-Diff drops PSNR from 51.55 to 51.32 dB; removing scale replay loss drops it to 50.97 dB.
Measured effects reported in the paper
| What was changed | Where | Measured | Effect |
|---|---|---|---|
| Use Prompt-SID instead of N2C | Synthetic denoising · Gaussian σ=25, Kodak | PSNR: 32.43 -> 32.41 | No clear effect |
| Use Prompt-SID instead of B2U | Prompt-SID · SIDD Benchmark | PSNR: 50.79 -> 51.02 | Helped |
| Use Prompt-SID instead of N2C | Fluorescence imaging denoising · 1 Hz | SNR: 15.65 -> 15.89 | Helped |
| Use Prompt-SID instead of N2C | Fluorescence imaging denoising · 3 Hz and 10 Hz | SNR: 16.28 -> 15.98; 16.14 -> 16.06 | Hurt |
| Use Prompt-SID instead of B2U | Fluorescence imaging denoising · 30 Hz | SNR: 21.12 -> 21.10 | No clear effect |
| Add RG-Diff and SAM prompt fusion (ablation) | Prompt-SID · SIDD | PSNR: 51.32 -> 51.55 | Helped |
| Add RG-Diff and SAM prompt fusion (ablation) | Prompt-SID · Kodak, Gaussian σ=25 | PSNR: 31.97 -> 32.41 | Helped |
| Add downsampled structural conditioning rather than Gaussian noise (ablation) | RG-Diff · SIDD | PSNR: 51.40 -> 51.55 | Helped |
| Add scale replay loss L_sc (ablation) | Prompt-SID · SIDD | PSNR: 50.97 -> 51.55 | Helped |
| Add scale replay loss L_sc (ablation) | Prompt-SID · Kodak, Gaussian σ=25 | PSNR: 32.01 -> 32.41 | Helped |
| Add diffusion representation loss L_diff (ablation) | Prompt-SID · SIDD | PSNR: 51.03 -> 51.55 | Helped |
| Add diffusion representation loss L_diff (ablation) | Prompt-SID · Kodak, Gaussian σ=25 | PSNR: 32.32 -> 32.41 | No clear effect |
Surprising findings
- The text claims a 0.32 dB gain over the N2C baseline on Set14 for sigma in [5,50], but the reported table shows Prompt-SID at 31.22 dB versus 31.41 dB for the baseline, a discrepancy.
- Supervised N2C baseline outperforms Prompt-SID on several Gaussian and Poisson settings in the tables, despite the paper's claim of superiority in eight of twelve settings.
Limitations
- Gains over the strongest self-supervised baselines are modest (often about 0.2 dB or less on synthetic data).
- Reported results on some settings are below supervised N2C, and some text claims are inconsistent with the tables.
Experimental setup
Datasets: ILSVRC2012 SIDD-Medium SRDtrans two-photon calcium imaging dataset
Benchmarks: Kodak BSD300 Set14 SIDD benchmark SIDD validation fluorescence two-photon calcium imaging
Metrics: PSNR SSIM SNR
Baselines: N2C CBM3D N2V NBR2NBR B2U ZS-N2N DT
Builds on: Noise2Noise Noise2Void Blind2Unblind NBR2NBR ZS-N2N
Closest papers by meaning
- Prompt-tuning Latent Diffusion Models for Inverse Problems (ICML 2024 · similarity 0.87)
- Denoising Diffusion Bridge Models (ICLR 2024 · similarity 0.87)
- Diff-Prompt: Diffusion-Driven Prompt Generator with Mask Supervision (ICLR 2025 · similarity 0.86)
- Deconstructing Denoising Diffusion Models for Self-Supervised Learning (ICLR 2025 · similarity 0.86)
- FreeControl: Efficient, Training-Free Structural Control via One-Step Attention Extraction (NeurIPS 2025 · similarity 0.86)
- OSCAR: One-Step Diffusion Codec Across Multiple Bit-rates (NeurIPS 2025 · similarity 0.86)
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